Document Detail

Clinical impact of stent construction and design in percutaneous coronary intervention.
MedLine Citation:
PMID:  15131529     Owner:  NLM     Status:  MEDLINE    
Convincing end point data demonstrating the anatomic and clinical superiority of stent placement compared with balloon angioplasty together with significant improvement in stenting technique and poststent management have resulted in an explosion in stenting procedures and the emergence of more than 40 stent types with disparate designs and material composition in clinical use. Structural nuances in design, composition, and coating of different stent models, however, have been shown to have a major influence on the risk of stent thrombosis, the degree of vessel wall injury, and subsequent intimal proliferation in the experimental model. There is now substantial amount of evidence to indicate that the same relationship between stent structural characteristics and vessel wall outcome holds true in humans. This article provides an up-to-date overview of the clinical impact of stent construction and design, including the clinical performance of drug-eluting stents.
Kean-Wah Lau; Koon-Hou Mak; Jui-Sung Hung; Ulrich Sigwart
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American heart journal     Volume:  147     ISSN:  1097-6744     ISO Abbreviation:  Am. Heart J.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-05-07     Completed Date:  2004-07-22     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  764-73     Citation Subset:  AIM; IM    
National Heart Centre, Singapore, Singapore.
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MeSH Terms
Biocompatible Materials
Coronary Disease / surgery*
Coronary Restenosis / prevention & control
Drug Delivery Systems
Paclitaxel / administration & dosage
Prosthesis Design
Sirolimus / administration & dosage
Stents* / adverse effects,  classification
Reg. No./Substance:
0/Biocompatible Materials; 33069-62-4/Paclitaxel; 53123-88-9/Sirolimus

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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