| Clinical impact and predictors of carotid artery in-stent restenosis. | |
| | |
MedLine Citation:
|
PMID: 22318354 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
To assess the incidence and clinical significance as well as predictors of in-stent restenosis (ISR) after carotid artery stenting (CAS) diagnosed with serial duplex sonography investigations. We analyzed 215 CAS procedures that had clinical and serial carotid duplex ultrasound investigations. The incidence of in-stent restenosis (ISR) and periprocedural as well as long-term clinical complications were recorded. The influence of an ISR on clinical complication was analyzed using Kaplan-Meier curves and clinical risk factors for the development of an ISR with multivariate logistic regression. During a median follow-up time of 33.4 months (interquartile range 15.3-53.7) an ISR of ≥70% was detected in 12 (6.1%) of 215 arteries (mean age of 68.1 ± 9.8 years, 71.6% male). The combined stroke and death rate during long-term follow-up was significantly higher in the group with an ISR [odds ratio (OR): 3.59, 95% confidence interval (CI): 1.50-8.59, p = 0.004]. After applying multivariate logistic regression analysis contralateral carotid occlusion (OR 10.11, 95% CI 2.06-49.63, p = 0.004), carotid endarterectomy (CEA) restenosis (OR 8.87, 95% CI 1.68-46.84, p = 0.010) and postprocedural carotid duplex ultrasound with a PSV ≥120 cm/s (OR 6.33, 95% CI 1.27-31.44, p = 0.024) were independent predictors of ISR. ISR after CAS during long-term follow-up is associated with a higher proportion of clinical complications. A close follow-up is suggested especially in those patients with the aforementioned independent predictors of an ISR. Against the background of a lacking established treatment of ISR, these findings should be taken into account when offering CAS as a treatment alternative to CEA. |
| | |
Authors:
|
Katrin Wasser; Sonja Schnaudigel; Janin Wohlfahrt; Marios-Nikos Psychogios; Peter Schramm; Michael Knauth; Klaus Gröschel |
Related Documents
:
|
153714 - Development of pulmonary arterial changes in rats fed crotalaria spectabilis. 22619694 - Advances in the diagnosis and treatment of acute pulmonary embolism. 17823354 - Role of endothelium-derived cc chemokine ligand 2 in idiopathic pulmonary arterial hype... 22356534 - Tadalafil for the treatment of pulmonary arterial hypertension. 3172384 - Vein compression by arterial aneurysms. 2335834 - Therapeutic options for acute thrombosed in situ saphenous vein arterial bypass grafts. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-2-9 |
Journal Detail:
|
Title: Journal of neurology Volume: - ISSN: 1432-1459 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-2-9 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0423161 Medline TA: J Neurol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Regional and Social Disparities in Tobacco Use in the 2009 Microcensus: Results in the Population of...
Next Document: 3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts nove...