| Clinical impact of positron emission tomography (PET) with (18F)fluorodeoxyglucose (FDG) in head and neck tumours. | |
| | |
MedLine Citation:
|
PMID: 17364351 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
CONCLUSION: PET plays an important role in staging, on suspicion of recurrence and for detection of occult primary tumours in the head and neck. OBJECTIVE: Since 1998 we have used positron emission tomography (PET) with (18F)fluorodeoxyglucose (FDG) to assess selected patients. This procedure has often helped in making decisions on staging and treatment. PATIENTS AND METHODS: The case records of the first 80 patients (104 PET examinations) were studied retrospectively. RESULTS: A total of 39 examinations were performed for staging. PET detected all primary tumours except two (stage T1), and staging was adjusted after 13%. In all, 33 PET examinations were performed on suspicion of recurrent tumour. In 52% of these PET determined further treatments; in 21% PET had a direct impact on the surgical planning. In 18 patients with metastases from an occult primary tumour, PET detected 39% of those tumours; in 22% it was the sole modality to do so. No recurrences or second primary tumours were detected when PET was used for follow-up of clinically cured patients. Results were similar when squamous cell carcinomas (SCCs) were considered alone as compared to the complete material. The mean standardized uptake value (SUV) was higher for cases deemed tumour-positive than in negative cases. |
| | |
Authors:
|
Tomas Ekberg; Jens S?rensen; Mats Engstr?m; Erik Blomquist; Anders Sundin; Matti Anniko |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Acta oto-laryngologica Volume: 127 ISSN: 0001-6489 ISO Abbreviation: Acta Otolaryngol. Publication Date: 2007 Feb |
Date Detail:
|
Created Date: 2007-03-16 Completed Date: 2007-04-10 Revised Date: 2010-03-24 |
Medline Journal Info:
|
Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: Norway |
Other Details:
|
Languages: eng Pagination: 186-93 Citation Subset: IM |
Affiliation:
|
Department of Otorhinolaryngology and Head & Neck Surgery, University Hospital (Akademiska Sjukhuset), Uppsala, Sweden. tomas.ekberg@akademiska.se |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Aged, 80 and over Female Fluorodeoxyglucose F18 / diagnostic use* Head and Neck Neoplasms / radionuclide imaging*, secondary Humans Male Middle Aged Neoplasm Metastasis Neoplasm Recurrence, Local / radionuclide imaging Neoplasm Staging Neoplasms, Unknown Primary / radionuclide imaging Positron-Emission Tomography Radiopharmaceuticals / diagnostic use* Retrospective Studies Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
|
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clinical features of head and neck cancer patients with methicillin-resistant Staphylococcus aureus.
Next Document: Osteomyelitis in the head and neck.