Document Detail


Clinical and imaging observations of desmoid tumors left without treatment.
MedLine Citation:
PMID:  17260204     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Until now, surgical treatment has been the mainstay in the treatment of desmoid tumors, even though it is associated with a high recurrence rate. There have, however, been occasional case reports showing that desmoid tumors may spontaneously decrease in size or even disappear. PATIENTS AND METHODS: This is a retrospective review of 8 patients with abdominal (5) or extra-abdominal (3) desmoid tumors who were followed both clinically and with imaging techniques (sonography, CT or MRI). Mean follow-up time was 4.4 (0.8-7.5) years. Tumor volume was assessed in each investigation and followed over time. RESULTS: 3 tumors disappeared, 2 diminished in size, 1 did not change and 2 tumors became larger, 1 of which had tripled in volume at the latest follow-up. INTERPRETATION: Desmoid tumors have probably been overtreated in the past. Many of them tend to regress spontaneously.
Authors:
B P Mikael Dalén; Mats Geijer; Henry Kvist; Peter M Bergh; Björn U P Gunterberg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta orthopaedica     Volume:  77     ISSN:  1745-3674     ISO Abbreviation:  Acta Orthop     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2007-01-29     Completed Date:  2007-02-05     Revised Date:  2009-12-11    
Medline Journal Info:
Nlm Unique ID:  101231512     Medline TA:  Acta Orthop     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  932-7     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics, Sahlgrenska University Hospital, Göteborg, Sweden. mikael.dalen@vgregion.se
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Diagnostic Imaging
Female
Fibromatosis, Abdominal / diagnosis*
Fibromatosis, Aggressive / diagnosis*
Follow-Up Studies
Humans
Male
Middle Aged
Neoplasm Regression, Spontaneous*
Retrospective Studies
Soft Tissue Neoplasms / diagnosis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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