| Clinical imaging and high-resolution ultrasonography in melanocytoma management. | |
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MedLine Citation:
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PMID: 20714362 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: To demonstrate the utility of high resolution 20 MHz ophthalmic ultrasound in serial follow-up of optic nerve head melanocytoma patients. METHODS: This study is a retrospective review of 30 patients with melanocytoma of the optic nerve head studied with echography. All patients were evaluated with standard ophthalmic A-scan and B-scan ultrasonography and 10 (33%) underwent high-resolution ultrasound. RESULTS: Sixty-two percent (62%) of patients had dome-shaped lesions on ultrasound, twenty-eight percent (28%) presented with mild elevations. The maximum elevation of any lesion was 2.6 mm. The vast majority (89%) of lesions had medium or high internal reflectivity and 89% demonstrated avascularity. Mean follow-up for all patients was nearly 7 years. High-resolution ultrasound enabled enhanced accuracy for detection of lesion dimensions and documentation of growth and possible malignant transformation. CONCLUSIONS: In this study, we demonstrate a new and important role for the use of ultrasound in this disease as a complementary tool in identifying and following patients with high-risk growth characteristics. These tumor characteristics can be accurately detected with 10 MHz ultrasound in conjunction with standardized A-scan and better differentiated with the 20 MHz technology. Use of these modalities can aid in distinguishing the melanocytomas that grow from choroidal melanomas and can prevent unnecessary treatments. |
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Authors:
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Daniel Gologorsky; Amy C Schefler; Fiona J Ehlies; Paul A Raskauskas; Yolanda Pina; Basil K Williams; Timothy G Murray |
Publication Detail:
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Type: Journal Article Date: 2010-08-09 |
Journal Detail:
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Title: Clinical ophthalmology (Auckland, N.Z.) Volume: 4 ISSN: 1177-5483 ISO Abbreviation: Clin Ophthalmol Publication Date: 2010 |
Date Detail:
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Created Date: 2010-08-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101321512 Medline TA: Clin Ophthalmol Country: New Zealand |
Other Details:
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Languages: eng Pagination: 855-9 Citation Subset: - |
Affiliation:
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Dartmouth Medical School, Hanover, New Hampshire; |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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