Document Detail


Clinical, hormonal and semiological data in adult men operated in childhood for hypospadias.
MedLine Citation:
PMID:  575328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Examination of 16 adult men operated in childhood for hypospadias revealed signs of moderate injury of the male genital system. It appears that accessory sexual glands were mainly responsible for the observed abnormalities. Since testicular position and size, serum testosterone and FSH levels were normal it seems that hypospadias and the accompanied disturbances are connected with reduction of responsiveness of target tissues to androgen stimuli rather, than with lesion of the testicle. The coexistence of normal serum testosterone and elevation of serum LH suggests the decrease of sensitivity of hypothalamic or pituitary receptors to negative feedback influence of androgens. The consciousness of sexual inadequacy noted in some cases was mainly of emotional character.
Authors:
J Zubowska; J Jankowska; K Kula; I Owczarczyk; A Garbowska-Górska
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Endokrynologia Polska     Volume:  30     ISSN:  0423-104X     ISO Abbreviation:  Endokrynol Pol     Publication Date:    1979 Nov-Dec
Date Detail:
Created Date:  1980-05-14     Completed Date:  1980-05-14     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0370674     Medline TA:  Endokrynol Pol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  565-73     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Follicle Stimulating Hormone / blood
Follow-Up Studies
Humans
Hypospadias / surgery*
Luteinizing Hormone / blood
Male
Penis / physiopathology
Sexual Dysfunction, Physiological / diagnosis*,  etiology
Sperm Count
Testis / physiopathology
Testosterone / blood
Chemical
Reg. No./Substance:
58-22-0/Testosterone; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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