Document Detail

Clinical, hormonal and biochemical features of menopausal women in Ibadan, Nigeria.
MedLine Citation:
PMID:  2558555     Owner:  NLM     Status:  MEDLINE    
As a result of the general lack of information about the menopause in Nigeria this study was conducted to determine the prevalence of climacteric symptoms in a cohort of healthy perimenopausal women and also to evaluate the hormonal and biochemical profile of the subjects. Seventeen menopausal and 19 premenopausal women aged 40 years or more were interviewed and had venepuncture and collection of 24-h urine samples. Plasma from the blood samples was used for the assay of LH, FSH, progesterone, 17 beta-oestradiol, calcium and cholesterol while urinary calcium was determined from the 24-h urine samples. The data revealed a significant difference in the prevalence of the symptoms of vasomotor instability (hot flushes, palpitations and excessive sweating) among the menopausal group when compared with the premenopausal group. Furthermore, plasma gonadotrophin levels (LH and FSH) were significantly elevated while plasma oestradiol and progesterone levels were lower in the menopausal women than in the premenopausal group. With regards to the biochemical indices evaluated, only 24-h urinary calcium levels were found to be significantly different for the two groups, with higher levels in the menopausal women. The significance of these findings and the need for adequate screening and treatment of selected menopausal women are discussed.
E O Otolorin; I Adeyefa; B O Osotimehin; T Fatinikun; O Ojengbede; J O Otubu; O A Ladipo
Related Documents :
24534555 - Apoe gene and exceptional longevity: insights from three independent cohorts.
22055015 - Multiple biological pathways link cognitive lifestyle to protection from dementia.
14617885 - Differences in health characteristics between native japanese and japanese-americans.
16930875 - Menopause characteristics of women with physical disabilities from poliomyelitis.
25025585 - A birth cohort analysis of the incidence of adenocarcinoma of the uterine cervix in the...
17241625 - Polycystic ovary syndrome and risk of uterine leiomyomata.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  African journal of medicine and medical sciences     Volume:  18     ISSN:  0309-3913     ISO Abbreviation:  Afr J Med Med Sci     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-02-16     Completed Date:  1990-02-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7801013     Medline TA:  Afr J Med Med Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  251-5     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, University College Hospital, Ibadan, Nigeria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Attitude to Health
Climacteric / blood,  ethnology,  physiology*
Estradiol / blood
Gonadotropins / blood
Middle Aged
Progesterone / blood
Reg. No./Substance:
0/Gonadotropins; 50-28-2/Estradiol; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The influence of undergraduate clinical training on the attitude of medical students to rural medica...
Next Document:  Ventilatory pulmonary function study in healthy young Nigerian adults.