Document Detail


Clinical and histopathologic correlation in patients with dilated cardiomyopathy. Value of force-velocity product.
MedLine Citation:
PMID:  2810763     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate the relation between cardiac function and myocardial damage in patients with dilated cardiomyopathy (DCM), we compared echocardiographic parameters and histopathologic findings of the biopsied myocardium in 50 cases with DCM. As wall motion is much influenced by the increased afterload in cases with large ventricles, we generated a new contractile parameter, Force-Velocity Product (FVP). FVP was defined as the result obtained by multiplying mean circumferential fiber shortening velocity by noninvasive end-systolic wall stress. FVP correlated with percent fibrosis in the myocardium, which was reflected by no other echocardiographic parameter. We also evaluated the prognostic values of the echocardiographic and histopathologic parameters. FVP had the highest value among them. We conclude that FVP is a very useful clinical parameter, with the further advantage of being obtained noninvasively.
Authors:
H Kurozumi; Y Yokota; H Fukuzaki
Related Documents :
18549503 - Hyperthyroidism as a reversible cause of right ventricular overload and congestive hear...
668753 - The recurrence risk in congenital heart disease.
20708743 - True hermaphroditism: first evidence of an ovotestis in a cetacean species.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese heart journal     Volume:  30     ISSN:  0021-4868     ISO Abbreviation:  Jpn Heart J     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-12-07     Completed Date:  1989-12-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401175     Medline TA:  Jpn Heart J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  431-41     Citation Subset:  IM    
Affiliation:
First Department of Internal Medicine, Kobe University School of Medicine, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Biopsy
Cardiomyopathy, Dilated / diagnosis*,  pathology
Echocardiography
Female
Humans
Male
Middle Aged
Myocardial Contraction*
Myocardium / pathology*
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  [Pharmacokinetic and clinical studies of cefteram pivoxil granule in the pediatric field].
Next Document:  Reversal of rest asynergy during exercise in patients with coronary artery disease.