| Clinical and histological evaluation of laser myocardial revascularization. | |
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MedLine Citation:
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PMID: 10148964 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies exploring methods to revascularize the ischemic myocardium through increasing the collateral circulation were conducted by many investigators before the advent of myocardial revascularization by aortocoronary bypass grafting. Present alternatives, including surgical intervention, balloon angioplasty, thrombolytic therapy, and medical management, are the treatment of choice for the majority of patients. There are, however, a number of patients who do not respond to conventional management strategies. A clinical protocol was designed to assess the efficacy of transmural revascularization by creating CO2 laser channels in the ischemic areas of the left ventricle. Channels were made from the epicardial surface of the heart, through the ventricle, to the endocardium. Patients entered in the study were candidates for bypass grafting, but because of the pathology of the coronary artery system, bypass grafting alone would have resulted in incomplete revascularization. Postoperative thallium stress tests and left ventriculography indicate that channels have remained patent and that they perfuse the myocardium. Myocardial revascularization by laser channels may offer a viable adjunct in the treatment of ischemic heart disease. |
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Authors:
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M Mirhoseini; S Shelgikar; M Cayton |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical laser medicine & surgery Volume: 8 ISSN: 1044-5471 ISO Abbreviation: J Clin Laser Med Surg Publication Date: 1990 Jun |
Date Detail:
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Created Date: 1992-08-27 Completed Date: 1992-08-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9006547 Medline TA: J Clin Laser Med Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 73-7 Citation Subset: T |
Affiliation:
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Heart & Lung Institute of Wisconsin, Milwaukee. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Coronary Disease / surgery* Female Follow-Up Studies Heart Ventricles Humans Laser Therapy* / methods Male Middle Aged Myocardial Revascularization / methods* |
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