Document Detail


Clinical and hemodynamic determinants of left ventricular dimensions.
MedLine Citation:
PMID:  6231007     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was designed to quantitate the influence of 20 clinical, hemodynamic, and volume determinants of left ventricular (LV) structure. Systemic hemodynamics, intravascular volume, and LV echocardiographic measurements were collected in a heterogeneous population of 171 patients. Stepwise multiple-regression analysis indicated that body weight and body-surface area were the most powerful determinants of LV chamber size, wall thickness, and muscle mass. Age, a pressure independent determinant of myocardial mass, had no influence on chamber size or LV function. Arterial pressure correlated best with the relative wall thickness and chamber volume. Intravascular volume was a major discriminator for chamber volume, LV mass, and velocity of circumferential fiber shortening. It is concluded that body weight, arterial pressure, intravascular volume, and age are each independent determinants of the LV dimension. Systolic pressure most closely correlated with relative wall thickness and thereby is the best predictor of degree of concentric LV hypertrophy.
Authors:
F H Messerli; K Sundgaard-Riise; H O Ventura; F G Dunn; W Oigman; E D Frohlich
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  144     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1984 Mar 
Date Detail:
Created Date:  1984-03-27     Completed Date:  1984-03-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  477-81     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aging
Cardiomegaly / pathology*
Echocardiography
Female
Hemodynamics*
Humans
Male
Middle Aged
Regression Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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