Document Detail

Clinical gynecologic features of pregnancy in Takayasu arteritis.
MedLine Citation:
PMID:  1360958     Owner:  NLM     Status:  MEDLINE    
Takayasu arteritis is a non-specific chronic inflammatory vascular disease of unknown etiology. Since the incidence of this disease in the child-bearing years is relatively high, the management of pregnancies with this disease is of great importance in clinical obstetrics. This study is aimed at discussing the maternal management and obstetrical outcome, based on the clinical data obtained from 23 pregnancies of 15 patients treated in our hospital in the past 12 years. Since the disease was in the active state, artificial abortions were conducted in four cases in the 1st trimester of pregnancy. Among the remaining 16 cases, 3, who exhibited neither hypertension nor other complications, vaginally delivered neonates weighing 2,660-3,100 g with Apgar scores of nine after 37 weeks' gestation. C-sections were performed for 13 patients who showed sustained hypertension or/and developed other vascular disorders. Their gestational periods ranged from 34 to 40 weeks and the body weight of the infants varied from 1,425 to 3,024 g. No adverse influence of pregnancy and delivery on Takayasu arteritis was detected in the puerperium of any patients. It is suggested that the state of Takayasu arteritis in early pregnancy and the magnitude of blood pressure elevation in the late gestational period are the most critical and definitive factors in determining the management of pregnancy of a patient with Takayasu arteritis. Cooperative managements by the specialists in obstetrics, internal medicine, and perinatology are required to provide a satisfactory clinical outcome.
T Aso; S Abe; T Yaguchi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Heart and vessels. Supplement     Volume:  7     ISSN:  0935-736X     ISO Abbreviation:  Heart Vessels Suppl     Publication Date:  1992  
Date Detail:
Created Date:  1993-01-12     Completed Date:  1993-01-12     Revised Date:  2008-02-26    
Medline Journal Info:
Nlm Unique ID:  8810802     Medline TA:  Heart Vessels Suppl     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  125-32     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Tokyo Medical and Dental University, School of Medicine, Japan.
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MeSH Terms
Abortion, Induced
C-Reactive Protein / analysis
Cesarean Section
Extraction, Obstetrical
Infant, Newborn
Patient Care Team
Pregnancy Complications, Cardiovascular / diagnosis*,  therapy
Prenatal Care
Takayasu Arteritis / classification,  diagnosis*,  therapy
Reg. No./Substance:
9007-41-4/C-Reactive Protein

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