Document Detail

Clinical first myocardial infarction: coronary artery disease and old infarcts in 53 consecutive fatal cases from a coronary care unit.
MedLine Citation:
PMID:  2789805     Owner:  NLM     Status:  MEDLINE    
The frequency and size of previous unrecognized myocardial infarction in patients with first clinical diagnosed acute myocardial infarction are unknown. In this study, 53 consecutive patients with clinical first acute myocardial infarction which proved fatal were studied postmortem. All showed acute infarction (inclusion criterium). Acute coronary thrombosis was found in 51 (96%). One-, two-, and three-vessel disease diagnosed by postmortem coronary angiography (diameter stenosis greater than or equal to 75%) was present in 17 (32%), 22 (42%), and 14 (26%), respectively. One or more old infarcts were found in 24 of the cases (45%) despite no history of previous myocardial infarction. Old infarcts were found in 86% of the hearts with three-vessel disease and in 55% of the hearts with two-vessel disease, but none were found in the hearts with one-vessel disease. The median weight of the old infarcts was 4 grams (range: 0.5 to 25 grams) corresponding to 5% (0.5 to 14%) of the ventricular myocardium. Thus, two- or three-vessel coronary artery disease and old infarcts are often present in patients dying from their clinical first acute myocardial infarction.
H R Andersen; E Falk; D Nielsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiovascular pathology     Volume:  2     ISSN:  0887-8005     ISO Abbreviation:  Am J Cardiovasc Pathol     Publication Date:  1989  
Date Detail:
Created Date:  1989-11-17     Completed Date:  1989-11-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8702438     Medline TA:  Am J Cardiovasc Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  315-9     Citation Subset:  IM    
Department of Cardiology, Skejby Sygehus, Denmark.
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MeSH Terms
Aged, 80 and over
Angina Pectoris / epidemiology,  mortality,  pathology
Coronary Disease / epidemiology,  mortality,  pathology*
Coronary Vessels / pathology
Middle Aged
Myocardial Infarction / epidemiology,  mortality,  pathology*
Myocardium / pathology
Time Factors

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