| Clinical features of GCA/PMR. | |
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MedLine Citation:
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PMID: 10948748 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Giant cell arteritis (GCA) is a common vasculitis of unknown cause that affects persons in middle age and older. Its incidence rises with increasing age. The inflammatory lesions involve larger arteries that contain an abundance of elastic tissue. Although cranial symptoms such as headache, tender scalp, jaw claudication and visual symptoms are common, the disease presents in many different fashions, often with symptoms not directly related to the arteries. These latter presentations include fever, severe malaise, polymyalgia rheumatica, high erythrocyte sedimentation rate and anemia, thrombocytosis, sore throat, and hepatic dysfunction. GCA appears to have a self-limited course, but is also characterized by relapses and recurrences. Visual loss due to occlusion of the optic arteries is the most important early manifestation and aortic aneurysm is the most important late complication. Patients respond promptly to varying doses of glucocorticoids but drug side effects are common. |
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Authors:
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G G Hunder |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinical and experimental rheumatology Volume: 18 ISSN: 0392-856X ISO Abbreviation: Clin. Exp. Rheumatol. Publication Date: 2000 Jul-Aug |
Date Detail:
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Created Date: 2000-11-21 Completed Date: 2000-12-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8308521 Medline TA: Clin Exp Rheumatol Country: ITALY |
Other Details:
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Languages: eng Pagination: S6-8 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine/Rheumatology, Mayo Clinic, Rochester, Minnesota 55901, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Giant Cell Arteritis
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diagnosis* Humans Polymyalgia Rheumatica / diagnosis* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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