| Clinical features and prognosis of herpetic anterior uveitis: a retrospective study of 111 cases. | |
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MedLine Citation:
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PMID: 20857175 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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To describe the clinical features and outcomes in patients with herpetic anterior uveitis. We reviewed the records of 111 patients with a clinical diagnosis of herpetic anterior uveitis seen at the Department of Ophthalmology, Istanbul Faculty of Medicine, from January 1996 to December 2006. Demographic and clinical features, recurrence rate, and visual outcome were analyzed. Fifty patients were male, 61 were female. Mean age at presentation was 39.2 ± 16.5 (6-74) years. Three atopic patients had bilateral involvement. Twelve patients had active or a past episode of herpes zoster ophthalmicus. Ocular findings were granulamatous anterior uveitis (93%), active keratitis or corneal scars (57%), elevated intraocular pressure (51%), iris atrophy (48%), distorted pupil (25%), and posterior synechiae (26%). Secondary glaucoma developed in two patients. None of the patients had posterior segment complications. The recurrence rate was 0.45/person-year. Topical corticosteroids and oral antiviral therapy were administered to all patients during active episodes. Long-term prophylactic oral acyclovir was used in 13%. Final visual acuity was worse than 0.5 in 17% of the involved eyes and was due to corneal scarring or cataract formation. Patients with iridocyclitis only had no permanent visual loss. Herpetic anterior uveitis is a recurrent granulomatous disease commonly associated with corneal involvement, iris atrophy, and transient intraocular pressure rise. Visual prognosis is good, especially in patients who have only anterior uveitis without corneal disease. |
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Authors:
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Ilknur Tugal-Tutkun; Berna Otük-Yasar; Emre Altinkurt |
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Publication Detail:
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Type: Journal Article Date: 2010-09-21 |
Journal Detail:
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Title: International ophthalmology Volume: 30 ISSN: 1573-2630 ISO Abbreviation: Int Ophthalmol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-11-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7904294 Medline TA: Int Ophthalmol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 559-65 Citation Subset: IM |
Affiliation:
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Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul University, Goz Hastaliklari A.D. Capa, 34390, Istanbul, Turkey. itutkun@istanbul.edu.tr |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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