| Clinical features and predictors for mortality in patients with infective endocarditis at a university hospital in Taiwan from 1995 to 2003. | |
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MedLine Citation:
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PMID: 16238819 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The clinical features and microbiological characteristics of 315 patients with definite or possible infective endocarditis (IE) from January 1995 to December 2003 were evaluated. There were 187 males and 128 females with a mean age of 51 years (range, 1 month to 92 years). Ninety-three patients (30%) had a diagnosis of valvular heart disease and 24 (8%) had received prosthetic valve replacement. Blood culture was negative in 62 patients (20%). Staphylococci (91 patients, 32%), including methicillin-susceptible Staphylococcus aureus (15%), methicillin-resistant S. aureus (11%), and coagulase-negative staphylococci (6%), were the most commonly encountered pathogens followed by viridans group streptococci (77 patients, 24%). Eight patients (25%) had various neurological, renal, embolic, and cardiac complications. Patients with neurological complications [odds ratio (OR) 8.175, P<0.001], nosocomial IE (OR 6.661, P<0.001), underlying malignancy (OR 4.993, P<0.001), elevated serum creatinine level (OR 3.132, P=0.001), or elevated WBC count (>15000/mm3) (OR 2.537, P=0.007) were at significantly increased risk of mortality. This study found mortality from IE was associated with several factors, among which neurological complications were the most hazardous. Patients with more than one risk factor had poorer prognosis. These results suggest the need for more aggressive management in patients with IE when multiple risk factors for mortality are identified. |
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Authors:
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C-N Hsu; J-Y Wang; C-D Tseng; J-J Hwang; P-R Hsueh; C-S Liau |
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Publication Detail:
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Type: Journal Article Date: 2005-10-20 |
Journal Detail:
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Title: Epidemiology and infection Volume: 134 ISSN: 0950-2688 ISO Abbreviation: Epidemiol. Infect. Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-04-26 Completed Date: 2006-06-08 Revised Date: 2010-09-20 |
Medline Journal Info:
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Nlm Unique ID: 8703737 Medline TA: Epidemiol Infect Country: England |
Other Details:
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Languages: eng Pagination: 589-97 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Bacteremia / microbiology Bacteria / isolation & purification Endocarditis, Bacterial / microbiology, mortality* Female Hospitals, University Humans Male Middle Aged Taiwan Time Factors |
| Comments/Corrections | |
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