Document Detail


Clinical features of patients with chronic pancreatitis complicated by bile duct strictures.
MedLine Citation:
PMID:  15239276     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/AIMS: Distal bile duct stenosis is relatively rare in patients with non-alcoholic chronic pancreatitis. METHODOLOGY: The clinical features of eight patients who had chronic pancreatitis complicated by bile duct strictures who underwent surgical treatments were reviewed. RESULTS: Ages ranged from 38 to 80 years, with a mean of 53.4 years. All but one patient were male. Six patients had moderate or slight epigastric pain. Five patients had obstructive jaundice and underwent biliary drainage. All patients had liver dysfunction due to biliary obstruction. Although four of the eight patients were heavy or moderate drinkers, none of the patients had a history of chronic pancreatitis. Stricture shapes of the common bile ducts were smooth and tapering in five patients, funnel-shaped in two, and rat-tail in one. Four patients underwent a pancreatoduodenectomy and one patient underwent a pylorus-preserving pancreatoduodenectomy for clinically suspected pancreatic malignancy that was later proven histopathologically to be chronic pancreatitis. The other three patients underwent a choledochoduodenostomy. There were no postoperative complications or deaths. During the follow-up period, all patients were asymptomatic. CONCLUSIONS: In conclusion, bile duct stricture potentially occurs not only in patients with alcoholic chronic pancreatitis but also in patients with nonalcoholic chronic pancreatitis. Furthermore, in some cases, it is impossible to differentiate chronic pancreatitis from pancreatic or periampullary malignancy.
Authors:
Fumio Kimura; Masaru Miyazaki; Hiroshi Itoh; Toshikazu Suwa; Toshiyuki Sugiura; Tokuzou Shinoda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  51     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:    2004 Jul-Aug
Date Detail:
Created Date:  2004-07-08     Completed Date:  2004-09-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  1191-5     Citation Subset:  IM    
Affiliation:
Department of General Surgery, Chiba University Graduate School of Medicine, Inohana, Chiba, Japan. kimura-f@umin.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Animals
Cholangiography
Choledochostomy
Chronic Disease
Common Bile Duct Diseases / etiology*,  physiopathology*,  radiography,  surgery
Constriction, Pathologic
Female
Follow-Up Studies
Humans
Liver / physiopathology
Male
Middle Aged
Pancreas / radiography
Pancreaticoduodenectomy
Pancreatitis / complications*,  physiopathology*,  radiography,  surgery
Pancreatitis, Alcoholic / complications,  physiopathology,  radiography,  surgery
Rats
Retrospective Studies
Tomography, X-Ray Computed
Treatment Outcome
Tumor Markers, Biological / blood
Chemical
Reg. No./Substance:
0/Tumor Markers, Biological

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