| Clinical features, pathogenesis, and computed tomographic characteristics of internal watershed infarction. | |
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MedLine Citation:
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PMID: 8248975 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Infarction in the internal border-zone region has been described radiologically and pathologically. The aim of this study was to define the clinical and pathophysiological correlates of internal watershed infarction. METHODS: Eighteen consecutive stroke patients with evidence of internal watershed infarction on computed tomography (CT) were studied. RESULTS: Two CT patterns were identified: 6 patients had confluent internal watershed infarction (CIWI), and 12 patients had partial internal watershed infarction (PIWI). Syncopal symptoms and/or documented hypotension were prominent in both groups. Patients with CIWI usually presented with stepwise onset of contralateral hemiplegia and recovered poorly; patients with PIWI usually had discrete episodes of brachiofacial sensorimotor deficit and good recovery. Both groups had evidence of cortical involvement as part of their clinical deficit. Severe carotid occlusive disease was seen in 10 patients, and 12 patients had evidence of transiently impaired cardiac output. Carotid disease (P < .001), cardiac disease (P < .01), and diabetes mellitus (P < .01) were more prevalent in patients with internal watershed infarction compared with our stroke population as a whole. CONCLUSIONS: Distinguishing internal watershed infarction from lacunar and other subcortical infarctions is important because the different pathological mechanisms demand different therapeutic strategies. |
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Authors:
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C F Bladin; B R Chambers |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Stroke; a journal of cerebral circulation Volume: 24 ISSN: 0039-2499 ISO Abbreviation: Stroke Publication Date: 1993 Dec |
Date Detail:
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Created Date: 1994-01-04 Completed Date: 1994-01-04 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0235266 Medline TA: Stroke Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1925-32 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Melbourne, Heidelberg Repatriation Hospital, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aged Cardiovascular Diseases / complications Carotid Artery Diseases / complications Cerebral Infarction / diagnosis, etiology, pathology, physiopathology* Diabetes Complications Female Humans Hypertension / complications Male Middle Aged Neuropsychological Tests Outcome Assessment (Health Care) Prognosis Risk Factors Smoking Tomography, X-Ray Computed |
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