Document Detail

Clinical features and outcome of acute otitis media in early infancy.
MedLine Citation:
PMID:  23245989     Owner:  NLM     Status:  Publisher    
OBJECTIVES: Acute otitis media (AOM) is common in childhood, but little is known on its course very early in infancy. In this study we investigated predisposing factors, clinical characteristics, and long-term outcomes of AOM in very young infants. METHODS: One hundred sixty infants aged less than 12 months with AOM hospitalized in two general hospitals during 2005-2006 were included in the study and followed-up for 3 years. Demographics, history, clinical manifestations, and further AOM episodes were studied in two infant groups defined by age at the first AOM episode: the very young infants, aged less than 60 days, and the older infants aged 61-365 days. RESULTS: Of the 147/160 infants successfully followed-up, 48 (32.7%) were aged less than 60 days and 99 (67.3%) were aged 61-365 days. The very young infants with AOM had more siblings (1.25 vs. 0.87; p=0.047) and used pacifiers less often (45.8% vs. 75.8%; RR 0.61, 95% CI 0.44-0.84; p=0.0007). Purulent otorrhea and irritability were more common in the early AOM onset group (52.1% vs. 32.3%; risk ratio (RR) 1.61, 95% confidence interval (CI) 1.09-2.39; p=0.03, and 60.4% vs. 38.4%; RR 1.57, 95% CI 1.12-2.21; p=0.01, respectively). AOM was complicated with meningitis in two infants, both in the very young group, and with mastoiditis in a further two infants, one in each group. No difference in further AOM episodes, use of ventilation tubes, or hearing impairment was observed between the two infant groups. CONCLUSIONS: AOM in the first 2 months of life may have different predisposing factors and clinical presentations, but not different recurrence rates or long-term outcomes.
Stavroula Ilia; Emmanouil Galanakis
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-13
Journal Detail:
Title:  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases     Volume:  -     ISSN:  1878-3511     ISO Abbreviation:  Int. J. Infect. Dis.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610933     Medline TA:  Int J Infect Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Department of Paediatrics, University of Crete, POB 2208, 71003 Heraklion, Greece.
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