Document Detail

Clinical features of confirmed versus suspected urogenital tuberculosis in region with extremely high prevalence of pulmonary tuberculosis.
MedLine Citation:
PMID:  19428090     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To compare the characteristics of confirmed vs suspected cases of urogenital tuberculosis (UGTB) in a geographic region with an extremely high prevalence of pulmonary tuberculosis. UGTB is notoriously difficult to diagnose. METHODS: A retrospective clinical record review was performed of 68 patients treated from March 1998 to July 2007. Group 1 (n = 45) had UGTB confirmed by microbiologic or histologic examination. Group 2 (n = 23) had a high suspicion of UGTB because of the clinical features, but no microbiologic or histologic confirmation. The data were collected and statistically analyzed using Student's t test for parametric data and Fisher's exact test for contingency tables (P < .05 was accepted as statistically significant). RESULTS: The clinical characteristics were not significantly different statistically, except for flank pain (14% vs 43%), renal cavitation (14% vs 44%), urolithiasis (0% vs 25%), and ureteral stricture formation (7% vs 39%) in groups 1 and 2, respectively. Anti-TB medication was given to 7 patients (30%) in group 2 despite the lack of a confirmed diagnosis. The outcome in terms of complications and renal function loss was not significantly different between the 2 groups. CONCLUSIONS: Flank pain, renal cavitation, urolithiasis, and ureteral stricture formation were significantly more common in the group with suspected UGTB than in those with confirmed UGTB. However, other clinical characteristics did not differ significantly between the 2 groups. In patients with clinical features highly suspicious of UGTB, it appears reasonable to institute anti-TB treatment, despite the lack of a confirmed diagnosis.
A D Zarrabi; C F Heyns
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-05-09
Journal Detail:
Title:  Urology     Volume:  74     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-01     Completed Date:  2009-08-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  41-5     Citation Subset:  IM    
Department of Urology, University of Stellenbosch and Tygerberg Hospital, Western Cape, South Africa.
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MeSH Terms
Middle Aged
Retrospective Studies
South Africa / epidemiology
Tuberculosis, Pulmonary / epidemiology*
Tuberculosis, Urogenital / diagnosis*
Young Adult
Comment In:
Urology. 2009 Jul;74(1):46   [PMID:  19567286 ]

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