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Clinical features of benign convulsions with mild gastroenteritis in Chinese infants.
MedLine Citation:
PMID:  23275105     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Benign convulsions occur in infants during the course of mild gastroenteritis. It is now recognized as a distinct clinical entity in many countries. However, its occurrence in China has not yet been widely recognized by Chinese pediatricians. METHODS: A retrospective study was conducted in 48 patients with convulsions between January 1, 2004 and December 31, 2009. RESULTS: The age of onset of gastroenteritis was between 13 months and 24 months in 34 patients (70.83%). The episodes occurred at a distinct autumn/winter peak (75%). The seizures mostly occurred within the first 5 days of gastroenteritis, especially within the first 3 days, peaking on day 2 (39.58%). Thirty-five patients (72.92%) had clustered seizures in their episodes. Most episodes were symmetric, generalized tonic-clonic (83.33%) and brief (93.75%). The seizures were induced by pain and/or crying in 19 (39.58%) patients. Stool culture was positive for rotavirus in 21 (53.85%) of the 39 patients. Twenty patients (20/41, 48.78%) still had clustered seizures after the administration of a single anticonvulsant drug. The seizures persisted even after the administration of two combined anticonvulsants in 5 (26.32%) of 19 episodes. All patients exhibited normal psychomotor development. CONCLUSIONS: Benign convulsions with mild gastroenteritis are not rare in China, and rotavirus infection is a major cause.
Authors:
Yun-Feng Wang; Zhong-Shu Zhou
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-29
Journal Detail:
Title:  World journal of pediatrics : WJP     Volume:  -     ISSN:  1867-0687     ISO Abbreviation:  World J Pediatr     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101278599     Medline TA:  World J Pediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China.
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