Document Detail

Clinical features of Black African neonates with Down's syndrome.
MedLine Citation:
PMID:  7555887     Owner:  NLM     Status:  MEDLINE    
Early reports indicated a low prevalence of Down's syndrome (DS) in black African children. More recent research demonstrates an incidence similar to, or higher than that reported to occur in First World populations. One of the possible reasons for underreporting of DS in Africa, appears to be the lack of recognition of the problem at birth. In this study, the musculoskeletal, central nervous system and craniofacial features are documented in 40 black DS neonates and 50 black control neonates without DS, and the findings are compared with those from a reported series of 37 caucasian DS and 40 healthy newborns. Musculoskeletal and central nervous system features were markedly similar in black and caucasian infants. However, the craniofacial features of the African DS newborns approximated more closely those of the normal African neonates, than was the case in the caucasian DS and normal neonates. This finding may partially explain the underreporting of DS in this population, and it emphasizes the need for a clinical awareness of DS and for complete clinical examination to identify affected infants.
A L Christianson; J G Kromberg; E Viljoen
Related Documents :
7861317 - Subgroup differentiation and subgroup bias among latinos as a function of familiarity a...
18789147 - A population-based study of race-specific risk for placental abruption.
2788747 - Urban-suburban differences in the incidence of low birthweight in a metropolitan black ...
15376807 - Infants can rapidly form new categorical representations.
22311127 - Hispanic infants with cystic fibrosis show low cftr mutation detection rates in the ill...
487517 - Disturbed maternal bereavement following infant death.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  East African medical journal     Volume:  72     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-10-24     Completed Date:  1995-10-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  KENYA    
Other Details:
Languages:  eng     Pagination:  306-10     Citation Subset:  IM    
Department of Human Genetics and Developmental Biology, Faculty of Medicine, University of Pretoria, Republic of South Africa.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Africa / epidemiology
African Continental Ancestry Group*
Case-Control Studies
Down Syndrome / epidemiology,  genetics*,  pathology*,  prevention & control
European Continental Ancestry Group
Infant, Newborn

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Road traffic accidents in Kenya: an epidemiological appraisal.
Next Document:  Lagos "area boys and girls" in rehabilitation: their substance use and psychosocial profiles.