Document Detail


Clinical feasibility of Açai (Euterpe olerácea) pulp as an oral contrast agent for magnetic resonance cholangiopancreatography.
MedLine Citation:
PMID:  19820489     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: We evaluate the effectiveness of the Amazonian fruit pulp from Euterpe olerácea (popularly named Açaí) as a negative oral contrast agent applied to clinical routine. The use of such contrasts is particularly important in magnetic resonance cholangiopancreatography (MRCP) to reduce overlapping. MATERIALS AND METHODS: We administered Açaí pulp to 5 nonsymptomatic subjects and 35 patients submitted to unspecific abdominal MR imaging, intending to set up optimal protocol. In 8 MRCP examinations, contrast and image effects were assessed and graded blindly by 2 independent radiologists. Quantitative analysis was performed by Wilcoxon test as to verify the potential of the Açaí to eliminate overlap signal over the pancreaticobiliary tract. Adverse effects and subject tolerance were also addressed. RESULTS: The Açaí pulp elicited a local brightness decrease in T2-weighted images. The depiction of gallbladder, common bile duct, ampulla of Vater, and pancreatic duct was markedly improved after Açaí ingestion because of the suppression of the overlapping from bowel loops and gastric content (P < 0.01). All patients considered Açaí palatable, and no side effect was registered. CONCLUSIONS: The Açaí pulp can be used routinely in MRCP studies as a natural, safe, and inexpensive negative oral contrast agent with high efficacy and patient acceptance.
Authors:
Tiago Arruda Sanchez; Jorge Elias; Luiz Alberto Colnago; Luiz Ernesto de Almeida Troncon; Ricardo Brandt de Oliveira; Oswaldo Baffa; Dráulio Barros de Araujo
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  33     ISSN:  1532-3145     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-10-12     Completed Date:  2009-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  666-71     Citation Subset:  IM    
Affiliation:
Departmento de Física e Matemática, FFCLRP, Universidade de São Paulo, Ribeirão Preto, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adult
Aged
Arecaceae*
Cholangiopancreatography, Magnetic Resonance / methods*
Choledocholithiasis / diagnosis*,  ultrasonography
Contrast Media / administration & dosage*,  diagnostic use*
Feasibility Studies
Humans
Male
Middle Aged
Patient Acceptance of Health Care
Plant Preparations / administration & dosage*,  diagnostic use*
Prospective Studies
Retrospective Studies
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Plant Preparations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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