Document Detail

Clinical expressions of food allergy.
MedLine Citation:
PMID:  12839112     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The perception, by both the public and health professionals, of the clinical expressions of food allergy (FA) varies widely, from one extreme of nonexistence to another extreme of causing almost every ailment. Critical investigations in recent years led to a better clarification, as well as a reasonable classification, of FA manifestations. OBJECTIVE: To provide a differential diagnosis of adverse reactions to foods and a classification of well proven FA manifestations. DATA SOURCES: Reviews and original articles published in peer-reviewed journals, as well as classic textbooks on FA. RESULTS: FA can affect several body systems. The gastro-intestinal tract is probably the most affected organ, but it does not always exhibit overt symptoms. Cutaneous manifestations are next in frequency, and in some studies are the most frequent perhaps because they are visible. Respiratory symptoms as sole manifestations of FA are less common, but have high frequency in children with atopic dermatitis. Systemic anaphylaxis has been responsible for sudden fatalities, although the exposure was often to minute quantities of the offending food. Other rare manifestations have been reported and are probably underdiagnosed. CONCLUSIONS: FA is defined as the immunologically mediated adverse reactions to foods. It can be expressed in a wide array of clinical manifestations, ranging from simple gastro-intestinal, cutaneous, or respiratory symptoms to fatal anaphylaxis. Studies are needed to verify some rare or anecdotal manifestations that have been reported but are still considered controversial.
Sami L Bahna
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology     Volume:  90     ISSN:  1081-1206     ISO Abbreviation:  Ann. Allergy Asthma Immunol.     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-07-03     Completed Date:  2003-08-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9503580     Medline TA:  Ann Allergy Asthma Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  41-4     Citation Subset:  IM    
Department of Pediatrics, Allergy & Immunology Section Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130-3932, USA.
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MeSH Terms
Diagnosis, Differential
Food Hypersensitivity / classification,  diagnosis,  etiology*

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