| Clinical experience with infants with Robin sequence: a prospective study. | |
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MedLine Citation:
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PMID: 11294545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To study the clinical course of patients with Robin sequence (RS) during the first 6 months of life. DESIGN: A longitudinal prospective study of children with RS. SETTING: Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru-SP, Brazil, 1997 and 1998. Patients: Sixty-two children were studied from hospital admission to 6 months of age. Thirty-three (53.2%) presented with probable isolated RS (PIRS), 25 (40.3%) presented with syndromes or other malformations associated with RS, and 4 (6.5%) presented with RS with neurological involvement. INTERVENTIONS: The type of respiratory tract obstruction was defined by nasopharyngoscopy. The patients with type 1 and type 2 obstruction underwent nasopharyngeal intubation (NPI), and glossopexy was indicated in patients with type 1 obstruction who did not show clinical improvement with this procedure. Tracheostomy was indicated in patients with type 2 obstruction who did not show a good course after NPI, in patients with type 1 obstruction who did not show good course after glossopexy, and in patients with type 3 and type 4 obstruction. RESULTS: Prone position treatment (PPT) or NPI was the definitive treatment in 25 cases (75.8%) of PIRS and in 13 cases (52%) of syndromes or other malformations. Among the children with type 1 obstruction, 24 (51.1%) were submitted exclusively to PPT and 12 (25.5%) to NPI. With the type 2 groups, only one (12.5%) received PPT, and three (37.5%) were treated exclusively with NPI. All 15 infants treated exclusively with NPI (24.4%) presented with good weight, length, and neuromotor development. CONCLUSIONS: Most patients with PIRS and type 1 obstruction improved without surgical intervention. NPI should be the initial treatment in all patients with RS with type 1 and type 2 obstruction who present with important respiratory and feeding difficulties. |
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Authors:
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I L Marques; T V de Sousa; A F Carneiro; M A Barbieri; H Bettiol; M R Gutierrez |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association Volume: 38 ISSN: 1055-6656 ISO Abbreviation: Cleft Palate Craniofac. J. Publication Date: 2001 Mar |
Date Detail:
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Created Date: 2001-04-10 Completed Date: 2001-05-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9102566 Medline TA: Cleft Palate Craniofac J Country: United States |
Other Details:
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Languages: eng Pagination: 171-8 Citation Subset: D; IM |
Affiliation:
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Hospital de Reabilitação de Anomalias Craniofaciais da Universidade de São Paulo, Bauru, SP, Brazil. ilza_marques@uol.com.br |
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| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Multiple Airway Obstruction / classification, physiopathology*, therapy Body Height Body Weight Child Development Endoscopy Follow-Up Studies Humans Infant Infant, Newborn Intubation, Intratracheal Longitudinal Studies Nasopharynx Pierre Robin Syndrome / classification, physiopathology*, therapy Prone Position Prospective Studies Survival Rate Tongue / surgery Tracheostomy Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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