Document Detail

Clinical experience with infants with Robin sequence: a prospective study.
MedLine Citation:
PMID:  11294545     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the clinical course of patients with Robin sequence (RS) during the first 6 months of life.
DESIGN: A longitudinal prospective study of children with RS.
SETTING: Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru-SP, Brazil, 1997 and 1998.
PATIENTS: Sixty-two children were studied from hospital admission to 6 months of age. Thirty-three (53.2%) presented with probable isolated RS (PIRS), 25 (40.3%) presented with syndromes or other malformations associated with RS, and 4 (6.5%) presented with RS with neurological involvement.
INTERVENTIONS: The type of respiratory tract obstruction was defined by nasopharyngoscopy. The patients with type 1 and type 2 obstruction underwent nasopharyngeal intubation (NPI), and glossopexy was indicated in patients with type 1 obstruction who did not show clinical improvement with this procedure. Tracheostomy was indicated in patients with type 2 obstruction who did not show a good course after NPI, in patients with type 1 obstruction who did not show good course after glossopexy, and in patients with type 3 and type 4 obstruction.
RESULTS: Prone position treatment (PPT) or NPI was the definitive treatment in 25 cases (75.8%) of PIRS and in 13 cases (52%) of syndromes or other malformations. Among the children with type 1 obstruction, 24 (51.1%) were submitted exclusively to PPT and 12 (25.5%) to NPI. With the type 2 groups, only one (12.5%) received PPT, and three (37.5%) were treated exclusively with NPI. All 15 infants treated exclusively with NPI (24.4%) presented with good weight, length, and neuromotor development.
CONCLUSIONS: Most patients with PIRS and type 1 obstruction improved without surgical intervention. NPI should be the initial treatment in all patients with RS with type 1 and type 2 obstruction who present with important respiratory and feeding difficulties.
I L Marques; T V de Sousa; A F Carneiro; M A Barbieri; H Bettiol; M R Gutierrez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association     Volume:  38     ISSN:  1055-6656     ISO Abbreviation:  Cleft Palate Craniofac. J.     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-04-10     Completed Date:  2001-05-10     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  9102566     Medline TA:  Cleft Palate Craniofac J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  171-8     Citation Subset:  D; IM    
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MeSH Terms
Abnormalities, Multiple
Airway Obstruction / classification,  physiopathology*,  therapy
Body Height
Body Weight
Child Development
Follow-Up Studies
Infant, Newborn
Intubation, Intratracheal
Longitudinal Studies
Pierre Robin Syndrome / classification,  physiopathology*,  therapy
Prone Position
Prospective Studies
Survival Rate
Tongue / surgery
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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