| Clinical experience with expanded use of the Ross procedure: a paradigm shift? | |
| | |
MedLine Citation:
|
PMID: 20583389 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND AND AIM OF THE STUDY: The study aim was to evaluate the short-term survival and functional outcome after the Ross procedure, with expanded inclusion criteria. METHODS: A total of 91 patients (21 females, 70 males; mean age 57.3 +/- 13.1 years; range: 0.1-74 years) underwent aortic valve replacement (AVR) with a Ross procedure at the authors' institution during the year 2007. The underlying valve diseases were stenosis in 60 patients, regurgitation in 17, and a mixed lesion in 14. Seven patients suffered from acute infective endocarditis, and in five patients the Ross operation was a reoperative procedure. Forty-four patients (48%) underwent surgery in association with concomitant procedures, which included predominantly coronary artery bypass surgery, mitral valve repair or replacement, or procedures of the ascending aorta. RESULTS: The mean cardiopulmonary bypass and aortic cross-clamp times were 147 +/- 31 min (range: 87-246 min) and 124 +/- 26 min (range: 73-195 min), respectively. Hospital mortality was 2.2%. No patient died during the follow up period. The aortic gradient was decreased from 5.1 +/- 2 mmHg at discharge, to 3.2 +/- 1 mmHg during follow up (p < 0.05); at the same times, the mean gradient of the decellularized tissue-engineered pulmonary valve was 2.8 +/- 1 mmHg and 2.7 +/- 1 mmHg, respectively. An echocardiographic examination of neo-aortic valve competence at 12 months revealed no or trivial aortic valve regurgitation in 80 patients, and mild (grade 1+) regurgitation in nine patients. No patient required reoperation of the autograft during follow up. Two patients underwent reconstruction of the right ventricular outflow tract. At 12 months' follow up, all patients enjoyed normal social interactions, were in NYHA functional class I or II, and free from complications. CONCLUSION: The Ross procedure can be offered as an alternative to standard prosthetic AVR with an excellent short-term outcome. The former inclusion/exclusion criteria for this procedure should be re-evaluated. |
| | |
Authors:
|
Alexander Weymann; Pascal M Dohmen; Herko Grubitzsch; Simon Dushe; Sebastian Holinski; Wolfgang Konertz |
Related Documents
:
|
19324139 - Effect of prosthesis-patient mismatch on long-term survival with mitral valve replaceme... 3493739 - A tri-institutional comparison of tissue and mechanical values using a patient-oriented... 19695889 - Clinical results of the medtronic mosaic porcine bioprosthesis up to 13 years. 3653119 - Long-term follow-up in 185 patients after mitral valve replacement with the lillehei-ka... 17720369 - Stentless aortic valve reoperations: a surgical challenge. 556399 - Influence of preoperative left ventricular function on results of homograft replacement... 12483629 - Gastroesophageal reflux after repair of congenital diaphragmatic hernia. 18054729 - Psychological response in spinal manipulation (prism): a systematic review of psycholog... 16540369 - The value of the endoscopic therapies in the treatment of rectal varices: a retrospecti... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of heart valve disease Volume: 19 ISSN: 0966-8519 ISO Abbreviation: J. Heart Valve Dis. Publication Date: 2010 May |
Date Detail:
|
Created Date: 2010-06-29 Completed Date: 2010-07-26 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9312096 Medline TA: J Heart Valve Dis Country: England |
Other Details:
|
Languages: eng Pagination: 279-85 Citation Subset: IM |
Affiliation:
|
Department of Cardiovascular Surgery, Charité - University Medicine Berlin, Campus Charité Mitte, Berlin, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Aortic Valve Insufficiency / surgery Aortic Valve Stenosis / surgery Bioprosthesis Child Child, Preschool Female Heart Valve Diseases / surgery* Hospital Mortality Humans Infant Male Middle Aged Patient Selection Prospective Studies Pulmonary Valve / transplantation* Reconstructive Surgical Procedures Suture Techniques Tissue Engineering Transplantation, Autologous Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Superior results following the Ross procedure in patients with congenital heart disease.
Next Document: The first fifty consecutive Bentall operations with a prefabricated tissue-valved aortic conduit: a ...