Document Detail

Clinical experience with a collagen-impregnated knitted Dacron vascular graft.
MedLine Citation:
PMID:  2145959     Owner:  NLM     Status:  MEDLINE    
This report describes our first clinical experience with collagen-impregnated Dacron grafts in the aortic position. Fifty-four consecutive patients (43 men and 11 women), average age 67.5 years (44-84), received 11 tube grafts and 23 bifurcated grafts for abdominal aortic aneurysm replacement, 17 bifurcated grafts for aortic occlusive disease, two grafts for aortic pseudoaneurysm, and one graft for thoracoabdominal aneurysm repair. No preclotting maneuvers were used and there was no blood leak from the fabric upon restoration of blood flow, in spite of the use of systemic heparin. The hospital transfusion rate averaged 1.2 units in patients with occlusive disease and 2.7 units in patients undergoing aneurysm resection, which were similar to the transfusion rate in patients receiving standard knitted grafts prior to this study. There were two postoperative deaths from a myocardial infarction and a cerebral hemorrhage and no perioperative thromboembolic events. During a follow-up averaging 41.5 months (26-59), there were two late graft limb thromboses secondary to outflow disease progression. One patient died of aspiration two months postoperatively. Four patients died secondary to cardiac disease in at 13 and 21 months with functioning grafts. The rest of the patients are alive with functioning grafts. We conclude that the collagen-impregnated Dacron graft obviates the need for preclotting maneuvers because of a zero functional porosity.
J A Freischlag; W S Moore
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of vascular surgery     Volume:  4     ISSN:  0890-5096     ISO Abbreviation:  Ann Vasc Surg     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-12-05     Completed Date:  1990-12-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8703941     Medline TA:  Ann Vasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  449-54     Citation Subset:  IM    
Department of Surgery, University of California, Los Angeles 90024.
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MeSH Terms
Aged, 80 and over
Aortic Aneurysm / surgery*
Aortic Diseases / surgery*
Arterial Occlusive Diseases / surgery*
Blood Vessel Prosthesis*
Follow-Up Studies
Graft Occlusion, Vascular
Middle Aged
Polyethylene Terephthalates
Reg. No./Substance:
0/Polyethylene Terephthalates; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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