Document Detail


Clinical experience with the 3F stentless aortic bioprosthesis: one-year follow up.
MedLine Citation:
PMID:  16901052     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND AIM OF THE STUDY: The 3F equine aortic bioprosthesis is a new stentless valve which is currently undergoing evaluation in a multicenter clinical trial and is considered to have superior hemodynamic performance. Herein is reported the authors' initial experience with the 3F valve, focusing on the hemodynamic performance of the device. METHODS: Between March 2002 and October 2003, 35 patients (age range 61-86 years) underwent aortic valve replacement with the 3F valve implanted in the subcoronary position. Evaluation of valve hemodynamic performance was assessed at discharge (postoperative day 5 +/- 2), at 3-6 months, and at 11-14 months' follow up by means of transthoracic echocardiography. The mean preoperative transvalvular pressure gradient was 63 +/- 14 mmHg. Before surgery, all patients were in NYHA class III or IV, despite aggressive medical treatment. Five patients underwent concomitant coronary artery bypass grafting. RESULTS: The implanted valve sizes ranged from 21 to 29 mm. There were no operative deaths and no major perioperative complications. After 12 months, mean pressure gradients for the 23-, 25-, 27- and 29-mm valves were 13, 13, 12 and 9 mmHg, respectively. Mean systolic pressure gradients and NYHA class were improved significantly after surgery. Mild signs of hemolysis and minimal central regurgitation were detected in some patients, but were of no clinical importance. Valve dysfunction or mechanical failure did not occur during the follow up period. CONCLUSION: Because of its flexible structure, the 3F aortic bioprosthesis is simple to implant, and no major adverse effects have been associated with such valve implantation at the authors' center. Transprosthetic gradients appeared to regress at 6-12 months' follow up. The durability of the device is yet to be established in ongoing long-term trials.
Authors:
J Linneweber; C Kossagk; M L Rogge; S Dushe; P Dohmen; W Konertz
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  15     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-08-11     Completed Date:  2006-11-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  545-8     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Surgery, Charité Universitätsmedizin, Berlin, Germany. joerg.linneweber@charite.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Animals
Aortic Valve*
Bioprosthesis*
Echocardiography
Evaluation Studies as Topic
Follow-Up Studies
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation
Hemodynamics
Horses
Humans
Middle Aged
Prospective Studies
Prosthesis Design
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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