Document Detail


Clinical experience of acute ferric chloride poisoning.
MedLine Citation:
PMID:  14513891     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ferric chloride is both a corrosive acid and iron compound; reports of poisoning in humans are rare. A retrospective study was conducted to evaluate patients with ferric chloride exposure reported to Poison Control Center-Taipei Veterans General Hospital during 1990-2001. After exclusion of incomplete records, 16 patients with ferric chloride exposure were analyzed (9 male, 7 female aged 12 to 70 y). The exposures were occupational inhalation (18.7%), suicidal ingestion (56.3%), and accidental ingestion (25.0%). Major symptoms and signs were nausea/vomiting (68.8%), sore throat (68.8%), abdominal pain (37.5%), oral ulcers (37.5%), metabolic acidosis (25.0%), aspiration pneumonia (18.8%), respiratory failure (12.5%), diarrhea (12.5%), and hypotension (12.5%). The severity of poisonings were fatal 6.3%, severe 18.8%, moderate 31.2%, mild 37.5%, and asymptomatic 6.3%. Deferoxamine therapy was given in 9 hospitalized patients with good recovery; however the fatal case did not receive deferoxamine due to rapid deterioration and a late diagnosis. The serum iron level known in 7 cases ranged from 40 to 2440 microg/dL. Ingestion of ferric chloride may result in serious morbidity and mortality. Inappropriate labeling and storage lead to accidental swallowing or misdiagnosis. Early diagnosis is important, especially in seriously poisoned patients.
Authors:
Ming-Ling Wu; Wei-Jen Tsai; Jiin Ger; Jou-Fang Deng
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Veterinary and human toxicology     Volume:  45     ISSN:  0145-6296     ISO Abbreviation:  Vet Hum Toxicol     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-09-29     Completed Date:  2003-11-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704194     Medline TA:  Vet Hum Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  243-6     Citation Subset:  IM    
Affiliation:
Division of Clinical Toxicology, Department of Medicine, Taipei Veterans General Hospital, Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adolescent
Adult
Aged
Child
Female
Ferric Compounds / blood,  poisoning*
Humans
Male
Medical Records
Middle Aged
Poison Control Centers
Poisoning / epidemiology*,  etiology
Retrospective Studies
Taiwan / epidemiology
Chemical
Reg. No./Substance:
0/Ferric Compounds; 7705-08-0/ferric chloride
Comments/Corrections
Comment In:
Vet Hum Toxicol. 2004 Jun;46(3):158-9   [PMID:  15171498 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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