Document Detail

Clinical and exercise echocardiographic findings in patients with mitral valve prolapse.
MedLine Citation:
PMID:  2332934     Owner:  NLM     Status:  MEDLINE    
To assess the relationship between left ventricular functional reserve and prognosis in patients with idiopathic mitral valve prolapse, ergometer exercise echocardiography was performed in 10 normal subjects and 30 patients with mitral valve prolapse having either mild, or no mitral regurgitation. These 30 patients with mitral prolapse were followed for 2 to 8 (mean 4.5) years. Increment of % fractional shortening during maximum exercise at the initial study in patients with mitral valve prolapse and normal subjects were 7 +/- 7 and 11 +/- 3%, respectively. Based on increment of % fractional shortening, patients with mitral valve prolapse were divided into 2 groups; Group I: 13 cases with delta% fractional shortening less than 5%, Group II: 17 cases with delta% fractional shortening greater than or equal to 5%. The incidence of cardiac symptoms was higher in Group I than in Group II (85 vs 41%, p less than 0.05). ST-T changes and life-threatening arrhythmias were more frequently observed in Group I. During the follow-up period, M-mode echocardiographic measurements did not vary in Group II, but left ventricular and left atrial dimensions increased significantly (p less than 0.05, p less than 0.01, respectively) and % fractional shortening decreased significantly (p less than 0.01) in Group I without any change in mitral regurgitation severity. Thus, some patients with mitral valve prolapse not having significant mitral regurgitation may develop progressive deterioration of the cardiac function, which may be predicted by exercise echocardiography.
Y Yokota; T Kumaki; T Miki; H Fukuzaki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  54     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-06-01     Completed Date:  1990-06-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  62-70     Citation Subset:  IM    
1st Department of Internal Medicine, Kobe University School of Medicine, Japan.
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MeSH Terms
Exercise Test
Follow-Up Studies
Heart Ventricles / physiopathology
Middle Aged
Mitral Valve Insufficiency / etiology
Mitral Valve Prolapse / complications,  physiopathology*

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