Document Detail

Clinical events following neuroangiography: a prospective study.
MedLine Citation:
PMID:  3686597     Owner:  NLM     Status:  MEDLINE    
Clinical events following cerebral angiography were prospectively evaluated in 1,002 procedures. The ischemic event rate between 0 and 24 hours was 1.3% (0.1% permanent). This incidence was higher (2.5%) in patients investigated for cerebrovascular disease, but the difference was not significant. In addition, 1.8% of the patients suffered ischemia (0.3% permanent) between 24 and 72 hours after angiography. Cerebral ischemic events occurred as a recurrence or worsening of a preexisting phenomenon. twice as often as de novo. All permanent ischemia was a worsening of a preexisting phenomenon. There was a significant increase in the incidence of neurologic events between 0 and 24 hours when the procedure lasted longer than 60 minutes and when there was systolic hypertension. Trends toward higher incidence were noted with the use of increased volume of contrast, with increased serum creatinine, when transient ischemic attacks or stroke were the indications, and when 3 or more catheters were used. The incidence of neurologic events between 24 and 72 hours increased significantly with the increase in the amount of contrast used, with age, and with diabetes. The occurrence of nonneurologic events (mostly hematomas) was significantly increased by multiple factors. This study shows that events can and do occur beyond the usual observation period of 24 hours but confirms the low risk of cerebral angiography when performed judiciously.
J E Dion; P C Gates; A J Fox; H J Barnett; R J Blom
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  18     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:    1987 Nov-Dec
Date Detail:
Created Date:  1988-01-20     Completed Date:  1988-01-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  997-1004     Citation Subset:  IM    
Department of Diagnostic Radiology, University Hospital, London, Ontario, Canada.
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MeSH Terms
Age Factors
Brain Ischemia / etiology*
Cerebral Angiography / adverse effects*
Cerebral Hemorrhage / etiology*
Cerebrovascular Disorders / etiology*
Contrast Media / administration & dosage
Diabetes Complications
Hypertension / complications
Ischemic Attack, Transient / etiology*
Prospective Studies
Risk Factors
Time Factors
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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