| Clinical evaluation of a modified coronally advanced flap alone or in combination with a platelet-rich fibrin membrane for the treatment of adjacent multiple gingival recessions: a 6-month study. | |
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MedLine Citation:
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PMID: 19186964 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The aim of this study was to determine whether the addition of an autologous platelet-rich fibrin clot (PRF) to a modified coronally advanced flap (MCAF) (test group) would improve the clinical outcome compared to an MCAF alone (control group) for the treatment of multiple gingival recessions. METHODS: Twenty subjects, presenting three adjacent Miller Class I or II multiple gingival recessions of similar extent on both sides of the mouth, were enrolled in the study. The mean recession value at baseline was 2.9 +/- 1.1 mm for test sites and 2.5 +/- 0.9 mm for control sites. Each patient was treated on both sides by an MCAF technique; the combination treatment (with a PRF membrane) was applied on the test side. Probing depth (PD), recession width, clinical attachment level (CAL), keratinized gingival width, and gingival/mucosal thickness (GTH) were measured at baseline and at 6 months post-surgery. Gingival recession was measured at baseline and at 1, 3, and 6 months post-surgery. RESULTS: Mean root coverage after 1, 3, and 6 months was 81.0% +/- 16.6%, 76.1% +/- 17.7%, and 80.7% +/- 14.7%, respectively, at the test sites and 86.7% +/- 16.6%, 88.2% +/- 16.9%, and 91.5% +/- 11.4%, respectively, at the control sites. Differences between the two groups were statistically significant at 3 and 6 months. At 6 months, complete root coverage was obtained at 74.6% of the sites treated with the control procedure but at only 52.2% of the experimental sites. At 6 months, the increase in GTH was statistically significant when comparing the test sites (from 1.1 +/- 0.3 mm at baseline to 1.4 +/- 0.5 mm at 6 months) to the control sites (from 1.1 +/- 0.3 mm at baseline to 1.1 +/- 0.3 mm at 6 months). In the case of PD, there was no significant difference between the two groups at 6 months, but a significant CAL gain in favor of the control group was observed at that time. CONCLUSIONS: MCAF is a predictable treatment for multiple adjacent Miller Class I or II recession-type defects. The addition of a PRF membrane positioned under the MCAF provided inferior root coverage but an additional gain in GTH at 6 months compared to conventional therapy. |
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Authors:
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Sofia Aroca; Tibor Keglevich; Bruno Barbieri; Istvan Gera; Daniel Etienne |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Journal of periodontology Volume: 80 ISSN: 0022-3492 ISO Abbreviation: J. Periodontol. Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-03 Completed Date: 2009-06-09 Revised Date: 2009-11-12 |
Medline Journal Info:
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Nlm Unique ID: 8000345 Medline TA: J Periodontol Country: United States |
Other Details:
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Languages: eng Pagination: 244-52 Citation Subset: D; IM |
Affiliation:
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sofiaaroca@mac.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Platelets Female Fibrin / therapeutic use* Gingiva / anatomy & histology Gingival Recession / drug therapy*, pathology, surgery* Gingivoplasty / methods* Humans Male Membranes, Artificial Middle Aged Surgical Flaps Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Membranes, Artificial; 9001-31-4/Fibrin |
| Comments/Corrections | |
Comment In:
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J Periodontol. 2009 Nov;80(11):1694-7; author reply 1697-9
[PMID:
19905939
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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