Document Detail

Clinical evaluation of lipids, lipoproteins and red blood cells sodium and potassium in patients with different grades of hypertension.
MedLine Citation:
PMID:  20510895     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To show that lipid and lipoprotein levels and cell sodium and potassium content and transport could change depending on the degree of hypertension. DESIGN AND METHODS: Forty-three hypertensive patients and 20 healthy subjects were recruited at the Cardiology and Biochemistry Departments of Tlemcen University Hospital Centre (Northwest of Algeria). RESULTS: Levels of CHOL, TG, PL, HDL-TG, LDLc, LDL-TG, LDL-PL, HDL2-TG and HDL3-TG were significantly higher in hypertensive patients than those in controls. HDL-PL levels were significantly lower in patients compared with controls and decreased according to the grade of hypertension. HDL2c, HDL2-PL and HDL3-TG and cell content and fluxes of sodium and potassium change gradually with higher grades of hypertension. CONCLUSIONS: Hypertensive patients with circulating lipid alterations are associated to ion cell content and transport abnormalities, which were worsened progressively with higher grade of hypertension.
Mourad Aribi; Hafida Merzouk; Mustapha Haddouche; Mohammed Benyoucef; Abdesselam Taleb; Mohammed Kendouci-Tani; Sid A Merzouk; Abderrahim Meziane
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Publication Detail:
Type:  Journal Article     Date:  2010-05-27
Journal Detail:
Title:  Clinical biochemistry     Volume:  43     ISSN:  1873-2933     ISO Abbreviation:  Clin. Biochem.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0133660     Medline TA:  Clin Biochem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  942-7     Citation Subset:  IM    
Copyright Information:
2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
Laboratory of Applied Molecular Biology and Immunology, Tlemcen Abou-Bekr Belkaïd University, Tlemcen 13000, Algeria.
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MeSH Terms
Erythrocytes / metabolism*
Hypertension / blood*,  metabolism
Lipids / blood*
Lipoproteins / blood*
Middle Aged
Potassium / blood*
Sodium / blood*
Reg. No./Substance:
0/Lipids; 0/Lipoproteins; 7440-09-7/Potassium; 7440-23-5/Sodium

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