Document Detail


Clinical evaluation of an enamel matrix derivative and a bioresorbable membrane in the treatment of degree III mandibular furcation involvement: a series of nine patients.
MedLine Citation:
PMID:  15446406     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study evaluated the effect of combining an enamel matrix derivative (EMD) and a bioresorbable membrane (GTR) in the surgical treatment of degree III mandibular furcation involvements. Nine patients with chronic periodontitis, presenting a total of 14 degree III mandibular furcation involvements, were included in the study. Surgical treatment of the defects was randomly assigned: (1) EMD (four defects); (2) GTR (three defects); and (3) EMD and GTR (seven defects). The degree of involvement was assessed prior to surgery and after 6 and 12 months by measuring the probing attachment level in the horizontal and vertical directions at the furcation site. At 6 and 12 months, partial closure of the involvements had occurred in approximately half of the treated furcations, and the vertical probing level consistently improved following all three treatment modalities. The results suggest that all three treatment modalities may improve healing following surgical treatment of degree III mandibular furcation involvements. However, further studies are needed to examine the clinical significance of these results and the histologic characteristics of the healing following application of EMD.
Authors:
Nikolaos Donos; Leif Glavind; Thorkild Karring; Anton Sculean
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The International journal of periodontics & restorative dentistry     Volume:  24     ISSN:  0198-7569     ISO Abbreviation:  Int J Periodontics Restorative Dent     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-09-27     Completed Date:  2004-10-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8200894     Medline TA:  Int J Periodontics Restorative Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  362-9     Citation Subset:  D    
Affiliation:
Department of Periodontology, Eastman Dental Institute, University College London, United Kingdom. N.Donos@eastman.ucl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Dental Enamel Proteins / therapeutic use*
Furcation Defects / surgery*
Guided Tissue Regeneration, Periodontal*
Humans
Mandibular Diseases / surgery*
Middle Aged
Statistics, Nonparametric
Chemical
Reg. No./Substance:
0/Dental Enamel Proteins; 0/enamel matrix proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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