Document Detail

Clinical and endoscopic features of Chinese reflux esophagitis patients.
MedLine Citation:
PMID:  18350624     Owner:  NLM     Status:  MEDLINE    
AIM: To analyze the clinical and endoscopic features of Chinese patients with reflux esophagitis (RE).
METHODS: A total of 1405 RE patients were analyzed retrospectively. Data on gender, age, presence/absence of H pylori infection and associated esophageal hiatal hernia were collected. Esophagitis was divided into different grades according to Los Angeles Classification.
RESULTS: Of 18823 patients, 1405 were diagnosed as RE. The ratio of male to female patients was 1.75:1 (P < 0.01). The mean age of male and female patients was significantly different (P = 0.01). The peak age at onset of the disease was 40-60 years. According to Los Angeles Classification, there were significant differences in the age of patients with grades A and B compared to patients with grades C and D (P < 0.01). Two hundred and seventy-seven patients were infected with H pylori, the infection rate was low (P < 0.01). Complication of esophageal hiatal hernia was found to be significantly associated with the severity of esophagitis and age in 195 patients (P < 0.01). Esophageal mucosa damages were mainly located at the right esophageal wall.
CONCLUSION: The peak age of onset of RE is 40-60 years and higher in males than in females. The mean age of onset of RE is lower in males than in females. The infection rate of H pylori is significantly decreased in patients with esophagitis. Old age and esophageal hiatal hernia are associated with more severe esophagitis. Right esophageal mucosal damage can occur more often in RE patients.
Wei Li; Shu-Tian Zhang; Zhong-Lin Yu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  14     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-19     Completed Date:  2008-07-28     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  1866-71     Citation Subset:  IM    
Department of Gastroenterology, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing Digestive Disease Center, Beijing 100050, China.
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MeSH Terms
Aged, 80 and over
Esophagitis, Peptic* / complications,  pathology,  physiopathology
Helicobacter Infections
Hernia, Hiatal / etiology
Middle Aged
Retrospective Studies

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