Document Detail

Clinical and endoscopic evidence of progression in 152 cases of equine recurrent laryngeal neuropathy (RLN).
MedLine Citation:
PMID:  11817549     Owner:  NLM     Status:  MEDLINE    
Examination of the long-term histories and clinical findings was performed in 351 horses suffering from recurrent laryngeal neuropathy (RLN) to examine for possible evidence of progression of this disorder. Fifty-two out of 351 cases (15%) had evidence of progression of the degree of laryngeal dysfunction over a median period of 12 months (range 1.5-48 months) with the onset of progression occurring at median age 7 years. In 30 cases, there was both endoscopic (median deterioration of 3 endoscopic grades; range 1-5 grades) and clinical evidence, with 29 (97%) of these horses concurrently developing sudden-onset, abnormal exercise-related respiratory 'noises' and 13 (43%) concurrently reporting reduced exercise performance. In the remaining 22 horses there was solely clinical evidence of RLN progression, including the sudden onset of abnormal exercise-related respiratory sounds in 16 (73%) and the worsening of such sounds in 6 (23%), associated with reduced exercise performance in 13 (59%) of these 22 cases. Endoscopically, 13 (59%) of the latter 22 cases had marked (total or almost total) RLN that did not appear compatible with their previous exercise-performance histories. This evidence of progression of RLN may be of particular significance in disputes concerning horses that are apparently normal at pre-purchase examination but are later shown to have RLN and also in the surgical treatment of less severe cases of RLN.
P M Dixon; B C McGorum; D I Railton; C Hawe; W H Tremaine; K Pickles; J McCann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Equine veterinary journal     Volume:  34     ISSN:  0425-1644     ISO Abbreviation:  Equine Vet. J.     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-01-30     Completed Date:  2002-05-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0173320     Medline TA:  Equine Vet J     Country:  England    
Other Details:
Languages:  eng     Pagination:  29-34     Citation Subset:  IM    
The Wellcome Trust Centre for Studies in Comparative Respiratory Medicine, The University of Edinburgh, Easter Bush Veterinary Centre, Midlothian, Scotland.
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MeSH Terms
Disease Progression
Follow-Up Studies
Horse Diseases / physiopathology*
Laryngoscopy / veterinary
Physical Conditioning, Animal
Recurrent Laryngeal Nerve / physiopathology*
Respiratory Sounds / physiopathology,  veterinary
Vocal Cord Paralysis / physiopathology,  veterinary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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