Document Detail


Clinical and endocrine features of ultrasound diagnosed polycystic ovary patients: the correlation between ovarian volume and androgen activity.
MedLine Citation:
PMID:  8474219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One hundred and twenty five patients with polycystic ovaries on ultrasonography and 17 controls with normal ovaries on ultrasound and regular ovulary cycles underwent clinical and endocrine evaluation. Of 125 ultrasound-diagnosed polycystic ovary patients (PCO) 49.6% complained about hirsutism, 55.2% had menstrual disturbances (46.4% oligomenorrhea, 8.8% amenorrhea), 23.2% had normal but irregular cycles and 50.4% had infertility. PCO patients had significantly higher mean serum LH, testosterone, androstenedione and DHEAS levels and higher mean ovarian volume compared with the control group. Sixty seven percent of PCO patients had enlarged ovaries and significantly higher mean serum LH, testosterone, androstenedione and DHEAS levels, compared with the PCO patients who had ovarian volume within normal range. There was a significant positive correlation between ovarian volume and serum LH, testosterone, androstenedione, DHEAS levels. Hirsutism, oligomenorrhea, irregular cycles were equally present in patients with normal ovarian volume and enlarged ovaries. These results illustrate the importance of ovarian volume measurement as an indicator of androgen production in PCO patients.
Authors:
N O Turhan; S Senoz; B Gulekli; G Ozaksit; H Oral; O Gokmen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  43     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-05-20     Completed Date:  1993-05-20     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  PAKISTAN    
Other Details:
Languages:  eng     Pagination:  4-6     Citation Subset:  IM    
Affiliation:
Department of Reproductive Endocrinology and Infertility, Zekai Tahir Burak Women's Hospital, Ankara, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Androgens / blood
Female
Humans
Luteinizing Hormone / blood
Ovary / pathology
Polycystic Ovary Syndrome* / blood,  pathology,  ultrasonography
Chemical
Reg. No./Substance:
0/Androgens; 9002-67-9/Luteinizing Hormone

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