Document Detail

Clinical and electrophysiological differences between patients with arrhythmogenic right ventricular dysplasia and right ventricular outflow tract tachycardia.
MedLine Citation:
PMID:  12727147     Owner:  NLM     Status:  MEDLINE    
AIMS: Radiofrequency catheter ablation is considered first line treatment for symptomatic patients with right ventricular outflow tract tachycardia (RVOT). The role of ablation in arrhythmogenic right ventricular dysplasia (ARVD) is more limited. As such, differentiating between the two conditions is essential. METHODS AND RESULTS: This study compared non-invasive findings, magnetic resonance images (MRI), invasive electrophysiological characteristics, results of ablation and long-term outcome in 50 consecutive patients with RVOT (33) or ARVD (17). Structural abnormalities were uniform in the ARVD group; in addition 18 (54%) of the RVOT tachycardia group had MRI abnormalities. At electrophysiological study the tachycardia in the ARVD group displayed features of re-entry in over 80%, but behaved with a triggered automatic basis in 97% with RVOT. Ablation was complete or partial success in 12 (71%) patients with ARVD and ventricular tachycardia (VT) recurred in eight (48%). In the RVOT patients, ablation was a complete success in 97% with recurrent VT in 6%. Long-term success in the RVOT patients was 95% in both patients with and without MRI abnormalities. CONCLUSIONS: Electrophysiological characterization can differentiate ARVD from RVOT. The finding of abnormalities on MRI does not have any bearing on arrhythmia mechanism, acute or long-term success of RFA.
D O'Donnell; D Cox; J Bourke; L Mitchell; S Furniss
Related Documents :
12727147 - Clinical and electrophysiological differences between patients with arrhythmogenic righ...
19386617 - Head-up tilt induced syncope and adenosine a2a receptor gene polymorphism.
2121017 - Electrophysiologic and electrocardiographic effects, efficacy and safety of encainide i...
3989117 - Activation mapping in patients with coronary artery disease with multiple ventricular t...
7124407 - Detection of staphylococcus aureus antibodies in patients with s. aureus infections and...
19809217 - A case of early phase dialysis associated effusive constrictive pericarditis with disti...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European heart journal     Volume:  24     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-02     Completed Date:  2003-06-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  England    
Other Details:
Languages:  eng     Pagination:  801-10     Citation Subset:  IM    
Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Arrhythmogenic Right Ventricular Dysplasia / diagnosis,  physiopathology*,  therapy
Catheter Ablation / methods*
Echocardiography / methods
Follow-Up Studies
Magnetic Resonance Angiography
Middle Aged
Tachycardia, Ventricular / diagnosis,  physiopathology*,  therapy
Ventricular Dysfunction, Right / diagnosis,  physiopathology*,  therapy
Comment In:
Eur Heart J. 2003 May;24(9):787-8   [PMID:  12727145 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Apoptosis in heart: basic mechanisms and implications in cardiovascular diseases.
Next Document:  Development and prospective validation of a risk stratification system for patients with syncope in ...