| Clinical and electrophysiologic results after intracameral lidocaine 1% anesthesia: a prospective randomized study. | |
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MedLine Citation:
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PMID: 10519578 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the efficacy and safety of intracameral lidocaine in cataract surgery compared to peribulbar anesthesia. DESIGN: A prospective, randomized, controlled study. PARTICIPANTS: A total of 200 consecutive cataract patients (200 eyes) participated. INTERVENTION: Eyes were randomly assigned to two groups: one group received 0.15 ml intracameral 1% unpreserved lidocaine combined with topical anesthesia (oxybuprocaine); the other group received 6 ml prilocaine peribulbar before phacoemulsification with sclerocorneal tunnel incision. MAIN OUTCOME MEASURES: Duration of surgery was measured; implicit time and amplitudes of the b-waves of the photopic electroretinogram (ERG) potentials (single-flash ERG and the 30-Hz flicker ERG) were recorded; frequencies of intraoperative problems, complications, intraoperative, and postoperative pain were evaluated. RESULTS: After lidocaine anesthesia combined with topical anesthesia, similar complications were found, longer operation time (P < 0.001), and significantly better visual acuity immediately after surgery (P < 0.001). The ERG amplitudes were not significantly reduced after 0.15-ml intracameral lidocaine half an hour after surgery (P > 0.05). CONCLUSION: Intracameral lidocaine 1% combined with topical anesthesia can be recommended as an alternative procedure to peribulbar anesthesia in cataract surgery with corneoscleral tunnel incision. |
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Authors:
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N Anders; T Heuermann; K Rüther; C Hartmann |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Ophthalmology Volume: 106 ISSN: 0161-6420 ISO Abbreviation: Ophthalmology Publication Date: 1999 Oct |
Date Detail:
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Created Date: 1999-10-18 Completed Date: 1999-10-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802443 Medline TA: Ophthalmology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1863-8 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, Charté, Faculty of Humboldt University, Berlin, Germany. norbert.anders@charite.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anesthesia, Local / methods* Anesthetics, Combined / administration & dosage* Anesthetics, Local / administration & dosage* Electroretinography Humans Lens Implantation, Intraocular Lidocaine / administration & dosage* Orbit Pain Measurement Pain, Postoperative Patient Satisfaction Phacoemulsification* Procaine / administration & dosage, analogs & derivatives* Prospective Studies Retina / drug effects, physiology Visual Acuity |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Combined; 0/Anesthetics, Local; 137-58-6/Lidocaine; 59-46-1/Procaine; 99-43-4/benoxinate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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