Document Detail

Clinical and electrophysiologic results after intracameral lidocaine 1% anesthesia: a prospective randomized study.
MedLine Citation:
PMID:  10519578     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the efficacy and safety of intracameral lidocaine in cataract surgery compared to peribulbar anesthesia. DESIGN: A prospective, randomized, controlled study. PARTICIPANTS: A total of 200 consecutive cataract patients (200 eyes) participated. INTERVENTION: Eyes were randomly assigned to two groups: one group received 0.15 ml intracameral 1% unpreserved lidocaine combined with topical anesthesia (oxybuprocaine); the other group received 6 ml prilocaine peribulbar before phacoemulsification with sclerocorneal tunnel incision. MAIN OUTCOME MEASURES: Duration of surgery was measured; implicit time and amplitudes of the b-waves of the photopic electroretinogram (ERG) potentials (single-flash ERG and the 30-Hz flicker ERG) were recorded; frequencies of intraoperative problems, complications, intraoperative, and postoperative pain were evaluated. RESULTS: After lidocaine anesthesia combined with topical anesthesia, similar complications were found, longer operation time (P < 0.001), and significantly better visual acuity immediately after surgery (P < 0.001). The ERG amplitudes were not significantly reduced after 0.15-ml intracameral lidocaine half an hour after surgery (P > 0.05). CONCLUSION: Intracameral lidocaine 1% combined with topical anesthesia can be recommended as an alternative procedure to peribulbar anesthesia in cataract surgery with corneoscleral tunnel incision.
N Anders; T Heuermann; K Rüther; C Hartmann
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Ophthalmology     Volume:  106     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-10-18     Completed Date:  1999-10-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1863-8     Citation Subset:  IM    
Department of Ophthalmology, Charté, Faculty of Humboldt University, Berlin, Germany.
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MeSH Terms
Anesthesia, Local / methods*
Anesthetics, Combined / administration & dosage*
Anesthetics, Local / administration & dosage*
Lens Implantation, Intraocular
Lidocaine / administration & dosage*
Pain Measurement
Pain, Postoperative
Patient Satisfaction
Procaine / administration & dosage,  analogs & derivatives*
Prospective Studies
Retina / drug effects,  physiology
Visual Acuity
Reg. No./Substance:
0/Anesthetics, Combined; 0/Anesthetics, Local; 137-58-6/Lidocaine; 59-46-1/Procaine; 99-43-4/benoxinate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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