Document Detail

Clinical efficiency and safety analysis of transcatheter closure of multiple atrial septal defects in adults.
MedLine Citation:
PMID:  19301294     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Transcatheter closure of atrial septal defects (ASDs) is currently a reliable alternative to surgery, even though challenging in patients with multiple ASDs. HYPOTHESIS: The aim of this study was to evaluate the clinical efficiency and safety of transcatheter closure in multiple ASDs. METHODS: Multiple ASDs were diagnosed by transthoracic echocardiography (TTE) or transesophageal echocardiography (TEE). The occlusive condition and distance between 2 adjacent ASDs were measured by TTE examination. Then, the number and size of the occluder(s) was determined. TTE examinations were performed after transcatheter closure as follow-up. RESULTS: The transcatheter procedure was successful in 15 patients with multiple ASDs, using a single occluder in 9 patients and 2 occluders in the remaining 6 patients. Overall, 21 ASD occluders were implanted. During a follow-up period of 6 mo to 5 y, a slight residual shunt was found in 1 patient without any symptoms; a moderate residual shunt was identified at the inferior vena cava and the occluder was removed by surgery 1 mo after procedure. Other complications, including endocarditis, arrhythmia, thromboembolism, and atrioventricular valve damage were not recorded in any of the 15 patients during the follow-up period. CONCLUSION: Transcatheter closure of multiple ASDs is safe and efficient. Two occluders are necessary for the distance of 2 ASDs more than 7 mm, and a single occluder is sufficient for those 7 mm or less.
Zhi-Yuan Song; Guo-Xiang He; Mao-Qin Shu; Hou-Yuan Hu; Shi-Fei Tong; Bo-Li Ran; Jian-Ping Liu; Yong-Hua Li; Tao Jing
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  32     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-03-25     Completed Date:  2009-05-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  130-4     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2009 Wiley Periodicals, Inc.
Department of Cardiology, Southwest Hospital, Third Military Medical University, Chongqing, People's Republic of China.
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MeSH Terms
Heart Catheterization / methods*
Heart Septal Defects, Atrial / therapy*
Middle Aged
Treatment Outcome

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