| Clinical efficacy of Japanese traditional herbal medicine (Kampo) in patients with late-onset hypogonadism. | |
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MedLine Citation:
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PMID: 20143961 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: In addition to hormone replacement therapy, non-hormonal therapy, particularly Japanese traditional herbal medicine (Kampo), has been used to alleviate the various symptoms of female menopause. The efficacy and safety of Japanese traditional herbal medicine for male late-onset hypogonadism (LOH) are investigated. METHODS: One hundred fifty-one patients with LOH were treated via the administration of Japanese traditional herbal medicine. The most appropriate Japanese traditional herbal medicine was administered to patients according to their pathogenic alteration. After 4 weeks, the clinical efficacy was evaluated based on improvement of LOH symptoms and the score of the simplified menopausal index (SMI). Additionally, predictive factors of efficacy of Japanese traditional herbal medicine were analyzed. RESULTS: Among 151 patients with LOH, 63 (41.8%) achieved both relief from LOH symptoms and normalized SMI score (Excellent response group), whereas 44 (29.1%) achieved either relief from LOH symptoms or normalized SMI score (Fair). However, 44 (29.1%) patients displayed neither relief from LOH symptoms nor normalized SMI score (Poor). Adverse reactions were observed only in four (2.6%) patients. Patients displaying excess conditions and mild LOH symptoms appeared to be superior candidates for Japanese traditional herbal medicine. CONCLUSION: Japanese traditional herbal medicine is an effective and safe treatment for LOH. |
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Authors:
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Toshiyasu Amano; Tetsuya Imao; Katsurou Takemae |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The aging male : the official journal of the International Society for the Study of the Aging Male Volume: 13 ISSN: 1473-0790 ISO Abbreviation: Aging Male Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-19 Completed Date: 2010-12-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9808210 Medline TA: Aging Male Country: England |
Other Details:
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Languages: eng Pagination: 166-73 Citation Subset: IM |
Affiliation:
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Department of Urology, Nagano Red Cross Hospital, Japan. amanot@nagano-med.jrc.or.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age of Onset Aged Aged, 80 and over Female Humans Hypogonadism / drug therapy* Japan Male Medicine, Kampo* Middle Aged Phytotherapy / methods* Testosterone / blood Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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58-22-0/Testosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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