Document Detail

Clinical effects of continuous microwave for postoperative septic wound treatment: a double-blind controlled trial.
MedLine Citation:
PMID:  7661296     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Continuous microwave (CM) has already been shown to be effective in treating various pathologic states. The aim of this trial was to study the curative effect of this new physical method on the course of postoperative suppurative and inflammatory processes in patients who underwent abdominal surgery. PATIENTS AND METHODS: In this study, 141 patients with postoperative purulent wounds (predominantly caused by pyogenic Staphylococcus aureus) were randomized into two groups: 71 patients received local CM therapy (group A), and the other 70 patients received a placebo treatment using a similar but ineffective device (group B, controls). In this double-blind study, criteria for wound healing in both patient groups were evaluated. RESULTS: Results demonstrated that wound clearance was significantly accelerated in group A (treated with CM) compared with group B (controls): 5.6 +/- 0.6 versus 10.2 +/- 0.5 days (mean +/- standard deviation), respectively. Similarly, initial epithelization was significantly forced in group A compared with group B: 7.0 +/- 0.4 versus 12.8 +/- 0.6 days, respectively; and granulation appeared after 4.9 +/- 0.2 versus 8.7 +/- 0.4 days of postoperative treatment, respectively. Daily decrease of wound surface area was significantly higher in group A than in group B (7.1% versus 3.2%). On the fifth postoperative day of treatment, the number of microorganisms was considerably lower (10(5) per gram of tissue) in patients treated with CM than in controls. CONCLUSIONS: The results of this controlled clinical trial suggest that low-intensity CM is an effective postoperative treatment of purulent wounds after abdominal surgery. Further investigations may elucidate the underlying mechanisms in detail and optimize the curative effects in surgical practice.
N N Korpan; T Saradeth
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  American journal of surgery     Volume:  170     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1995 Sep 
Date Detail:
Created Date:  1995-09-29     Completed Date:  1995-09-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  271-6     Citation Subset:  AIM; IM    
Department of General Surgery, State Medical University of Kiev, Kiev City Center of Liver, Bile Ducts and Pancreas Surgery, Ukraine.
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MeSH Terms
Aged, 80 and over
Double-Blind Method
Microwaves / therapeutic use*
Middle Aged
Staphylococcal Infections / radiotherapy
Surgical Wound Infection / radiotherapy*
Wound Healing

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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