| Clinical and economic evaluation of the trellis thrombectomy device for arterial occlusions: preliminary analysis. | |
| | |
MedLine Citation:
|
PMID: 14981448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: This preliminary study examined the technical efficacy, safety, and cost of treating arterial occlusions with a single device that combines pharmacologic and mechanical thrombolysis. METHODS: The technical success, bleeding complications, and costs for the first 26 consecutive patients in whom lower extremity ischemia was treated with the Trellis infusion catheter (TIC) were analyzed. Procedure time, thrombolytic infusion time, technical success, bleeding complications (major and intracranial hemorrhage), interventional suite time, and 30-day amputation-free survival were evaluated. RESULTS: 15 of 26 patients (58%) who received treatment with the TIC had acute arterial occlusions, and 11 of 26 patients (42%) had nonacute arterial occlusions. Nineteen of 26 patients (73.1%) received treatment of an infrainguinal occlusion, and 7 of 26 patients (26.9%) received treatment of a suprainguinal occlusion. Lower extremity native arteries were treated in 18 of 26 patients (69%), and lower extremity bypass grafts in 8 of 26 patients (31%). The technical success rate with TIC treatment was 92%, and the 30-day amputation-free survival rate was 96%. There was no difference in technical success or amputation-free survival rate between acute versus nonacute arterial occlusions, native artery versus bypass grafts, and suprainguinal versus infrainguinal arterial occlusions. Procedure time was 2.1 +/- 0.9 hours, and infusion time was 0.3 +/- 0.2 hours. There were no bleeding complications; however, 3 of 26 patients (11.5%) required further intervention to treat distal embolization. The overall mean cost for patients with TIC treatment was $3216 +/- $1740. CONCLUSIONS: Early results of TIC treatment in patients with arterial occlusions suggest that it is as effective as traditional catheter-directed thrombolysis. Furthermore, there were no bleeding complications, likely the result of TIC requiring shorter procedure and infusion times. |
| | |
Authors:
|
Timur P Sarac; Daniel Hilleman; Frank R Arko; Christopher K Zarins; Kenneth Ouriel |
Related Documents
:
|
12185548 - Local intra-arterial thrombolysis in the carotid territory: does recanalization depend ... 12082198 - Use of the x-sixer catheter system in the treatment of acute thrombotic coronary occlus... 15485518 - New criteria based on st changes in 12-lead surface ecg to detect proximal versus dista... 20573478 - Practical use of duplex echo-guided recanalization of chronic total occlusion in the il... 6238048 - Optic neuropathy from the use of intracranial muslin. 12920678 - Endovascular repair of abdominal aortic aneurysms: the cleveland clinic experience with... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter Volume: 39 ISSN: 0741-5214 ISO Abbreviation: J. Vasc. Surg. Publication Date: 2004 Mar |
Date Detail:
|
Created Date: 2004-02-24 Completed Date: 2004-03-30 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 556-9 Citation Subset: IM |
Affiliation:
|
Department of Vascular Surgery, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA. SaracT@ccf.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Arterial Occlusive Diseases / complications, surgery* Catheterization / adverse effects*, economics, instrumentation Cost-Benefit Analysis Female Humans Ischemia / surgery* Lower Extremity / blood supply* Male Middle Aged Postoperative Hemorrhage / etiology Thrombectomy / economics, instrumentation* Thrombosis / complications, surgery* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Early adaptation of human lower extremity vein grafts: wall stiffness changes accompany geometric re...
Next Document: Helicobacter pylori seropositivity is associated with enhanced platelet activation in patients with ...