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Clinical and economic characteristics associated with direct costs of Alzheimer's, frontotemporal and vascular dementia in Argentina.
MedLine Citation:
PMID:  21044400     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
ABSTRACTBackground: The economic cost of dementia is high and can be predicted by cognitive and neuropsychiatric profiles. The differential costs of the various subtypes of dementia are unknown in Argentina, and this study therefore aimed to compare these costs.Methods: Patients with a diagnosis of dementia of Alzheimer-type (DAT), frontotemporal dementia (FTD) and vascular dementia (VaD), and their primary caregivers, were evaluated between 2002 and 2008.Results: 104 patients with dementia (DAT = 44, FTD = 34, VaD = 26) were screened and matched by age and educational level with 29 healthy subjects. Demographic variables showed no significant differences among dementia patients. The annual direct costs were US$4625 for DAT, US$4924 for FTD, and US$5112 for VaD (p > 0.05 between groups). In the post hoc analysis VaD showed higher hospitalization costs than DAT (p < 0.001). VaD exhibited lower medication costs than FTD (p < 0.001). DAT exhibited higher anti-dementia drug costs; FTD had higher psychotropic costs. In the multivariate analysis, depression, activities of daily living, and caregiver burden were correlated with direct costs (r2 = 0.76).Conclusions: The different dementia types have different costs. Overall, costs increased with the presence of behavioral symptoms, depression and functional impairment of activities of daily living.
Authors:
Galeno Rojas; Leonardo Bartoloni; Carol Dillon; Cecilia M Serrano; Monica Iturry; Ricardo F Allegri
Publication Detail:
Type:  Journal Article     Date:  2010-11-03
Journal Detail:
Title:  International psychogeriatrics / IPA     Volume:  23     ISSN:  1741-203X     ISO Abbreviation:  Int Psychogeriatr     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-03-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9007918     Medline TA:  Int Psychogeriatr     Country:  England    
Other Details:
Languages:  eng     Pagination:  554-61     Citation Subset:  IM    
Affiliation:
Memory Research Center, Department of Neurology, Hospital General Abel Zubizarreta, GCABA, Buenos Aires, Argentina.
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