Document Detail

Clinical differentiation of acute necrotizing from chronic nonsuppurative pancreatitis in cats: 63 cases (1996-2001).
MedLine Citation:
PMID:  12930084     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To characterize clinical, clinicopathologic, radiographic, and ultrasonographic findings in cats with histologically confirmed acute necrotizing pancreatitis (ANP) or chronic nonsuppurative pancreatitis (CP) and identify features that may be useful in the antemortem differentiation of these disorders. DESIGN: Retrospective study. ANIMALS: 63 cats with histologically confirmed ANP (n = 30) or CP (33). PROCEDURE: Medical records were reviewed for signalment, clinical signs, concurrent diseases, clinicopathologic findings, and results of radiography and ultrasonography. RESULTS: Cats in both groups had similar nonspecific clinical signs, physical examination findings, and radiographic and ultrasonographic abnormalities. Abdominal ultrasonographic abnormalities, including hypoechoic pancreas, hyperechoic mesentery, and abdominal effusion, were found in cats in both groups and, therefore, were not specific for ANP. Cats with CP were significantly more likely to have concurrent diseases than were cats with ANP (100 and 83%, respectively). Clinicopathologic abnormalities were similar between groups; however, serum alanine aminotransferase and alkaline phosphatase activities were significantly higher in cats with CP. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that ANP and CP in cats cannot be distinguished from each other solely on the basis of history, physical examination findings, results of clinicopathologic testing, radiographic abnormalities, or ultrasonographic abnormalities.
Jean A Ferreri; Erin Hardam; Susan E Kimmel; H Mark Saunders; Thomas J Van Winkle; Kenneth J Drobatz; Robert J Washabau
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  223     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-08-21     Completed Date:  2003-11-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  469-74     Citation Subset:  IM    
Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
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MeSH Terms
Cat Diseases / diagnosis*,  radiography,  ultrasonography
Chronic Disease
Diagnosis, Differential
Pancreas / pathology*,  radiography,  ultrasonography
Pancreatitis / diagnosis,  radiography,  ultrasonography,  veterinary*
Pancreatitis, Acute Necrotizing / diagnosis,  radiography,  ultrasonography,  veterinary*
Physical Examination / veterinary
Radiography, Abdominal / veterinary
Retrospective Studies
Serologic Tests / veterinary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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