| Clinical differences between metoclopramide- and antipsychotic-induced tardive dyskinesias. | |
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MedLine Citation:
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PMID: 1972649 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A patient with tardive dyskinesia dominated by pelvic thrusting movements is described. A retrospective review of the clinical features documented in patients with metoclopramide- and antipsychotic-induced tardive dyskinesias seen over a six year period demonstrated that the occurrence of pronounced pelvic thrusting and respiratory dyskinesias were significantly more common in the metoclopramide treated group. The occurrence of bucco-linguomasticatory movements, limb stereotypies or chorea, and mild truncal or abdominal rocking were not significantly different between the two groups. None of the tardive dystonia patients had metoclopramide as the causative agent. These findings will require confirmation in larger, better matched patient populations. Whether the differences relate to different pharmacologic profiles of drug action, patient populations exposed, or other factors, remains to be elucidated. |
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Authors:
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A E Lang |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques Volume: 17 ISSN: 0317-1671 ISO Abbreviation: Can J Neurol Sci Publication Date: 1990 May |
Date Detail:
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Created Date: 1990-07-31 Completed Date: 1990-07-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0415227 Medline TA: Can J Neurol Sci Country: CANADA |
Other Details:
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Languages: eng Pagination: 137-9 Citation Subset: IM |
Affiliation:
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Movement Disorders Clinic, Toronto Western Hospital, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antipsychotic Agents / adverse effects* Dyskinesia, Drug-Induced / physiopathology* Female Humans Metoclopramide / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 364-62-5/Metoclopramide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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