| Clinical differences between early-onset HELLP syndrome and early-onset preeclampsia during pregnancy and at least 6 months postpartum. | |
| | |
MedLine Citation:
|
PMID: 20022586 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: We sought to evaluate whether clinical and laboratory variables differ between former patients who had HELLP syndrome and former patients who had preeclampsia (PE) without HELLP. STUDY DESIGN: We compared early-onset HELLP (n = 75) with early-onset PE (n = 40) with respect to clinical features during the hypertensive complication and to metabolic, hemodynamic, and hemostatic variables determined at least 6 months postpartum. RESULTS: HELLP differed from PE by a borderline higher frequency of eclampsia (13% vs 3%) during the complication, and by a lower prevalence of hypertension (19% vs 33%), proteinuria (2% vs 23%), thrombophilia (6% vs 27%), obesity (9% vs 33%), hypertriglyceridemia (1% vs 15%), hyperglycemia (0% vs 11%), and elevated levels of fasting homocysteine (6% vs 21%) at least 6 months postpartum. CONCLUSION: Women with HELLP had fewer signs of abnormalities consistent with the metabolic syndrome and a 4-fold lower prevalence of thrombophilia as compared with PE women without HELLP. |
| | |
Authors:
|
Simone Sep; Jef Verbeek; Gerardus Koek; Luc Smits; Marc Spaanderman; Louis Peeters |
Related Documents
:
|
20827656 - Hellp syndrome with and without eclampsia. 8216106 - Standard parameters of preeclampsia: can the clinician depend upon them to reliably ide... 19103366 - Drug-induced hypersensitivity syndrome: drug reaction with eosinophilia and systemic sy... 18854806 - Hellp syndrome and placental inflammatory pathology. 12160976 - Dichloroacetate therapy in leigh syndrome with a mitochondrial t8993c mutation. 20567036 - Orthodontic and orthognathic management of a patient with apert syndrome: a case report. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-12-22 |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 202 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2010 Mar |
Date Detail:
|
Created Date: 2010-03-08 Completed Date: 2010-04-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 271.e1-5 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright 2010 Mosby, Inc. All rights reserved. |
Affiliation:
|
Department of Obstetrics and Gynecology, Maastricht University Medical Center, Maastricht, The Netherlands. simone.sep@og.unimaas.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Eclampsia / epidemiology Factor V / genetics Female HELLP Syndrome / epidemiology* Heart Rate Homocysteine / blood Humans Hypercholesterolemia / epidemiology Hyperglycemia / epidemiology Hypertension / epidemiology Hypertriglyceridemia / epidemiology Mutation Obesity / epidemiology Postpartum Period* Pre-Eclampsia / epidemiology* Pregnancy Proteinuria / epidemiology Prothrombin / genetics Thrombophilia / epidemiology |
| Chemical | |
Reg. No./Substance:
|
0/factor V Leiden; 454-28-4/Homocysteine; 9001-24-5/Factor V; 9001-26-7/Prothrombin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of recommended levels of physical activity on pregnancy outcomes.
Next Document: Early menstrual characteristics associated with subsequent diagnosis of endometriosis.