| Clinical diagnosis and treatment of epidermal chytridiomycosis in African clawed frogs (Xenopus tropicalis). | |
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MedLine Citation:
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PMID: 12102573 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An investigation was conducted to determine the cause of morbidity and mortality in a collection of 55 adult male Xenopus (Silurana) tropicalis at the University of California, Berkeley. More than 80% of affected frogs died during the epizootic. All frogs were anorectic and lethargic, had dark pigmentation and excess skin sloughing, and lacked a slime layer. Histologic examination revealed severe hyperplastic and spongiotic dermatitis associated with colonization of the stratum corneum by large numbers of zoosporangia diagnostic of Batrachochytrium dendrobatidis. Treatment with a commercial formalin/malachite green solution at a dilution of 0.007 ml/L of tank water for 24 h, repeated every other day for four treatments, eliminated the organism and was curative. These findings are indicative of epidermal chytridiomycosis as a primary cause of death in this collection of X. tropicalis. |
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Authors:
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John M Parker; Igor Mikaelian; Nina Hahn; Helen E Diggs |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Comparative medicine Volume: 52 ISSN: 1532-0820 ISO Abbreviation: Comp. Med. Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-07-09 Completed Date: 2002-12-19 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 100900466 Medline TA: Comp Med Country: United States |
Other Details:
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Languages: eng Pagination: 265-8 Citation Subset: IM |
Affiliation:
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Office of Laboratory Animal Care, University of California, Berkeley 94720, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animal Husbandry Animals Chytridiomycota / isolation & purification*, pathogenicity Dermatomycoses / diagnosis, therapy, veterinary* Formaldehyde / therapeutic use Male Rosaniline Dyes / therapeutic use Treatment Outcome Xenopus* |
| Chemical | |
Reg. No./Substance:
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0/Rosaniline Dyes; 10309-95-2/malachite green; 50-00-0/Formaldehyde |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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