Document Detail

Clinical diagnosis and treatment of epidermal chytridiomycosis in African clawed frogs (Xenopus tropicalis).
MedLine Citation:
PMID:  12102573     Owner:  NLM     Status:  MEDLINE    
An investigation was conducted to determine the cause of morbidity and mortality in a collection of 55 adult male Xenopus (Silurana) tropicalis at the University of California, Berkeley. More than 80% of affected frogs died during the epizootic. All frogs were anorectic and lethargic, had dark pigmentation and excess skin sloughing, and lacked a slime layer. Histologic examination revealed severe hyperplastic and spongiotic dermatitis associated with colonization of the stratum corneum by large numbers of zoosporangia diagnostic of Batrachochytrium dendrobatidis. Treatment with a commercial formalin/malachite green solution at a dilution of 0.007 ml/L of tank water for 24 h, repeated every other day for four treatments, eliminated the organism and was curative. These findings are indicative of epidermal chytridiomycosis as a primary cause of death in this collection of X. tropicalis.
John M Parker; Igor Mikaelian; Nina Hahn; Helen E Diggs
Related Documents :
14668313 - Cold-acclimation in peromyscus: temporal effects and individual variation in maximum me...
6165193 - The effect of short-term occlusion on the cutaneous flora in atopic dermatitis and psor...
21191143 - Bolus arginine supplementation affects neither muscle blood flow nor muscle protein syn...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Comparative medicine     Volume:  52     ISSN:  1532-0820     ISO Abbreviation:  Comp. Med.     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-07-09     Completed Date:  2002-12-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  100900466     Medline TA:  Comp Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  265-8     Citation Subset:  IM    
Office of Laboratory Animal Care, University of California, Berkeley 94720, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Animal Husbandry
Chytridiomycota / isolation & purification*,  pathogenicity
Dermatomycoses / diagnosis,  therapy,  veterinary*
Formaldehyde / therapeutic use
Rosaniline Dyes / therapeutic use
Treatment Outcome
Reg. No./Substance:
0/Rosaniline Dyes; 10309-95-2/malachite green; 50-00-0/Formaldehyde

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Electrocardiographic monitoring in the Göttingen minipig.
Next Document:  Persistent truncus arteriosus in a rhesus monkey (Macaca mulatta).