Document Detail

Clinical diagnosis of cardiac beriberi.
MedLine Citation:
PMID:  2305319     Owner:  NLM     Status:  MEDLINE    
The clinical features of 28 patients with biochemically proven cardiac beriberi were prospectively studied. Patients recruited over a 2-year-period fell into two groups: (i) those with signs of hyperdynamic circulation; and (ii) those presenting with heart failure and circulatory shock with or without metabolic acidosis. All patients showed a dramatic response to intravenous thiamine; in group 1 the hyperdynamic state resolved within hours and in group 2 there was an immediate rise in the blood pressure with gradual resolution of the acidosis in 6-8 hours. Two patients in whom the diagnosis was missed died soon after admission to hospital. A notable finding was that even in the presence of peripheral circulatory shock, patients with beriberi had preservation of the femoral pulses often with 'pistol shots' and femoral bruit; this finding has clinical value in the diagnosis of acute cardiovascular beriberi (shoshin beriberi).
D P Naidoo; V Gathiram; A Sadhabiriss; F Hassen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  77     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-03-29     Completed Date:  1990-03-29     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  125-7     Citation Subset:  IM    
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MeSH Terms
Acidosis, Respiratory / complications
Beriberi / complications,  diagnosis*
Blood Circulation
Cardiac Output, Low / diagnosis
Heart Diseases / diagnosis*,  etiology
Thiamine / administration & dosage
Thiamine Pyrophosphatase / diagnostic use
Transketolase / blood
Reg. No./Substance:
EC; EC 3.6.1.-/Thiamine Pyrophosphatase; X66NSO3N35/Thiamine
Comment In:
S Afr Med J. 1990 May 19;77(10):542   [PMID:  2343362 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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