| Clinical demonstration of skin mildness and suitability for sensitive infant skin of a new baby wipe. | |
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MedLine Citation:
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PMID: 19840302 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A cleansing baby wipe with sufficient pH buffering capacity may help to restore the pH balance of skin following exposure to urine and feces in the diaper environment and maintain skin health. OBJECTIVE: To evaluate the skin effects of a novel baby wipe formulation with increased pH buffering. SUBJECTS AND METHODS: A series of clinical studies was designed and conducted to evaluate the skin effects of the new baby wipe, including a 21-day cumulative skin irritation patch study in adults (n = 31), a 4-week study in babies with medically confirmed atopic dermatitis (n = 32), a 2-week study comparing skin pH of babies (n = 15) following use of wipes compared with water and wash cloth, a series of clinical skin pH measurements following fecal exposure and subsequent cleaning with different products (n = 50) and a study evaluating comfort of product application on irritated skin (n = 31). RESULTS: The wipes formulation was well-tolerated, even in babies with atopic dermatitis, and was more comfortable versus water and washcloth. Increased buffering capacity of a wet wipes lotion helps to maintain a physiologically balanced skin pH value in the diaper region. |
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Authors:
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Ralf Adam; Baerbel Schnetz; Petra Mathey; Marc Pericoi; Yves de Prost |
Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pediatric dermatology Volume: 26 ISSN: 1525-1470 ISO Abbreviation: Pediatr Dermatol Publication Date: 2009 Sep-Oct |
Date Detail:
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Created Date: 2009-10-20 Completed Date: 2010-01-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8406799 Medline TA: Pediatr Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 506-13 Citation Subset: IM |
Affiliation:
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Procter & Gamble Service GmbH, Schwalbach Technical Center, Schwalbach am Taunus, Germany. adam.r@pg.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Buffers Dermatitis, Atopic / prevention & control* Diaper Rash / prevention & control* Female Humans Hydrogen-Ion Concentration Hygiene Infant Infant Care* Male Middle Aged Patch Tests Skin Care / adverse effects, methods* Soaps / administration & dosage*, adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Buffers; 0/Soaps |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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