Document Detail


Clinical data for radiation embryology. Investigation programme 1967, report 1984.
MedLine Citation:
PMID:  4034928     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 1967 a prospective clinical study was started with the aim of providing optimum counselling for married couples who desire continuation of a pregnancy despite radiation exposure at an early stage as a result of X-ray diagnostics. Recommendations were devised as to whether an interruption of pregnancy should be applied for or not. These results were discussed repeatedly. Within the framework of the prospective study, embryological examinations were made in cases of interruption of pregnancy, and clinical and genetic examinations in cases of children who had been subject to radiation stress in utero. Up to July 1st 1984 nearly 200 cases of consultations have been or are being surveyed. The children were subjected to selected longterm examinations of up to 13 years. The results of cytogenetic, biochemical-genetic, clinical, and other examinations are considered and special characteristics of interesting cases are discussed. The conclusion was drawn that the recommendation to our patients to continue pregnancy in cases of exposure to radiation in utero below 0.1 Sv, was right. Furthermore the question arose of whether this dose limit could be increased. The study will be continued.
Authors:
K Neumeister; S Wässer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiation and environmental biophysics     Volume:  24     ISSN:  0301-634X     ISO Abbreviation:  Radiat Environ Biophys     Publication Date:  1985  
Date Detail:
Created Date:  1985-10-07     Completed Date:  1985-10-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0415677     Medline TA:  Radiat Environ Biophys     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  227-37     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Radiation-Induced / epidemiology,  etiology*,  genetics
Abortion, Induced
Dose-Response Relationship, Drug
Female
Fetus / radiation effects*
Follow-Up Studies
Germany, East
Humans
Infant, Newborn
Male
Pregnancy
Prenatal Exposure Delayed Effects
Prospective Studies
Radiation Dosage*
Radiation Tolerance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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